Pendotech

Osteotech, Inc.

Jack McMickle

James Francis Furey

Dennis C Annarelli

Nelson L Scarborough

Michael Dowd

Mark P Daugherty

Richard Holowczak

A multiple tangential flow filtration (TFF) apparatus includes a plurality of tangential flow filtration (TFF) systems, a support frame defining a plurality of stations for supporting individual (TFF) systems and a single controller for controlling the plurality of tangential flow filtration systems. Each of the systems include at least a product vessel, a tangential flow filtration (TFF) filter and a pump for circulating a flow of liquid between said product vessel and said filter.

Processing system for multiple tangential flow filtration stations in bioprocessing applications

Sensor fitting

One embodiment of the invention relates to a liner for a first pump housing in a fluid pump assembly. The fluid pump assembly includes a first pump housing, a second pump housing and a flexible diaphragm disposed between the first and second pump housings. The first pump housing includes a fluid access port for providing fluid communication between an inside housing chamber of the first pump housing and an outside of the first pump housing. The second pump housing is securely mated to the first pump housing. The second pump housing includes a biasing mechanism for selectively displacing a portion of the diaphragm toward the first pump housing. The liner of the invention includes a flexible member removeably secured inside the first pump housing. The liner also includes a first portion of the member being shaped to substantially conform to the interior dimensions of the inside housing chamber and a second portion of the member shaped to substantially conform to the fluid access port. The member forms an inner liner chamber inside the inside housing chamber. The member also includes a mating portion for securing the member to the diaphragm to form a seal there between. The inner liner chamber being in fluid communication with the displaceable portion of the diaphragm. Whereby the displacement of the portion of the diaphragm expels fluid from the inner liner chamber through the fluid access port.

Diaphragm pump liner for critical process applications

A process for fabricating shaped material from demineralized bone particles includes the steps of applying a liquid slurry of demineralized bone particles to a support, removing excess liquid form the demineralized bone particles to provide a cohering shaped mass of demineralized bone particles, and warming the shaped mass of demineralized bone particles at a predetermined temperature and for a predetermined time period. The resultant bone mass exhibits enhanced tensile strength and minimal bone particle disassociation upon rehydration thereby improving product handling and application at the operative site.

Process for producing flexible sheets from demineralized, elongate, bone particles

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Nazareth, PA, United States of America

Jack McMickle