Baker Cummins Pharmaceuticals, Inc.

Baker Norton Pharmaceuticals, Inc.

Jack Fishman

Elliot F Hahn

Fred P Sherman

Phillip Frost

David C Atkinson

Gregory A Smith

Jing J Lu

Jane Hsiao

John Arnold

Novel anti-viral compounds comprise phosphate-linked dimers of anti-viral nucleoside derivatives, or salts or esters of such nucleoside dimers. Pharmaceutical compositions containing the dimers and methods of treatment utilizing the same are disclosed.

Anti-viral compounds, dosage forms and methods

Aldosterone biosynthesis inhibitors having substantially no intrinsic antiandrogenic activity are disclosed as well as pharmaceutical compositions containing such compounds and methods of treatment utilizing these compositions.

Aldosterone biosynthesis inhibitor

A method of inducing anesthesia or conscious sedation while avoiding serious hypotensive episodes comprising the administration of a parenterally active benzodiazpine in conjunction with an opiate analgesic followed by the parenteral administation of from about 1 to about 3 mg of a long-acting pure narcotic antagonist. The antogonist may be administered during the time interval commencing immediately prior to the procedure and continuing until about 3-5 hours after administration of the opiate-benzodiazepine combination.

Method of safely providing anesthesia or conscious sedation

A method of treating a human or animal patient suffering from an arthritic disease or associated inflammatory disease comprises daily administration to such patient of from about 1 to about 100 mg of the narcotic antagonists nalmefene or naltrexone. The nalmefene or naltrexone may be administered in equally divided doses from one to four times daily, preferably by the oral route. Parental administration may be utilized where suitable.

Growing community of inventors

Miami, FL, United States of America

Jack Fishman