Parkinson's Institute

Leland Stanford Junior University

J William Langston

Renee Ann Reijo Pera

Theodore D Palmer

James Anthony Byrne

Branden John Cord

Ruksana Azhu Valappil

Blake Byers

Birgitt Schule

Ha Nam Nguyen

Birgitt Schüle

Maryka Quik

Donato Di Monte

Methods are provided for non-invasive early screening of a subject for a neurodegenerative disorder, by analyzing one or more parameters associated with the neurodegenerative disorder.

Diagnosis of neurodegenerative disorders

Methods of generating cell lines with a sequence variation or copy number variation of a gene of interest, methods of use thereof, and cell lines with a sequence variation or copy number variation of a gene of interest are provided.

Pluripotent cell lines and methods of use thereof

The invention provides compositions and methods utilizing a nicotinic receptor modulator, e.g., to reduce or eliminate a side effect associated with dopaminergic agent treatment. In some embodiments, the invention provides compositions and methods utilizing a combination of a dopaminergic agent and a nicotinic receptor modulator that reduces or eliminates a side effect associated with dopaminergic agent treatment.

Methods and compositions for reduction of side effects of therapeutic treatments

Growing community of inventors

Los Altos Hills, CA, United States of America

J William Langston