Caliper Technologies Corporation

Nanosys, Inc.

Caliper Life Sciences, Inc.

Other

Sandisk Corporation

Eastman Chemical Company

Samsung Electronics Co., Ltd.

Sharp Kabushiki Kaisha Corporation

Callper Life Sciences, Inc.

Applera Corporation

Caliper Technologies Corportion

J Wallace Parce

Anne R Kopf-Sill

Calvin Y H Chow

Andrea W Chow

Xiangfeng Duan

Michael R Knapp

Steven A Sundberg

Jian Chen

Luc J Bousse

Robert S Dubrow

Chunming Niu

David P Stumbo

William P Freeman

Stephen A Empedocles

Mihai A Buretea

Erik C Scher

Jeffery A Whiteford

Andreas Meisel

Theo Teofanov Nikiforov

Chao Liu

Tammy Burd Mehta

Linda T Romano

Calvin Y Chow

Jeffrey A Wolk

Ring-Ling Chien

Jay L Goldman

Vijendra Sahi

Morten Juel Jensen

Benjamin N Wang

Lawrence A Bock

Karen Chu Cruden

Paul Bernatis

Michael A Spaid

Joel Gamoras

Francisco A Leon

David Leslie Heald

Baixin Qian

Srikanth Ranganathan

Yaoling Pan

Kevin C Krogman

James M Hamilton

Steve Gallagher

Mingjun Liu

Shihai Kan

H Garrett Wada

Jonathan M Ziebarth

Samuel Edward Martin

Cheri X Y Pereira

Benjamin Wang

Siglinde Schmid

Melissa Fardy

Joseph E Kercso

Andrew W Toth

Madhuri Nallabolu

Adrienne D Kucma

Hiroshi Iwata

Akihide Shibata

Paul John Schuele

Hiroshi Ohki

Paul T Furuta

Kyu S Min

Jeffrey L Miller

John C Owicki

Richard J McReynolds

Steven James Gallagher

Katsumasa Fujii

Tetsu Negishi

Linh Nguyen

Marja Liisa Alajoki

Yasunobu Okada

Yung-Mae M Yao

Donald J Morrissey, Jr

Jian Feng Chen

Colin B Kennedy

Erik Freer

Francesco Lemmi

R Hugh Daniels

David Olmeijer

Josh Molho

Thomas Workman

Javier Anibal Farinas

Jill M Baker

Robert Enzerink

Sherri Biondi

William Edward Jarvis

Esther Li

Alice Fischer-Colbrie

Yevgeny Yurkovetsky

Anubhav Tripathi

Claudia B Jaffe

Calvin Y H Cho

Bob Dubrow

Tom Hood

Bill Freeman

Steven D White

Sansan Lin

Thomas Fong

Matthew B Kerby

C Nicholas Hodge

Christopher Bloxsom

An array of transportable particle sets is used in a microfluidic device for performing chemical reactions in the microfluidic device. The microfluidic device comprises a main channel and intersecting side channels, the main channel and side channels forming a plurality of intersections. The array of particle sets is disposed in the main channel, and the side channels are coupled to reagents. As the particle sets are transported through the intersections of the main channel and the side channels, reagents are flowed through the side channels into contact with each array member (or selected array members), thereby providing a plurality of chemical reactions in the microfluidic system.

Manipulation of microparticles in microfluidic systems

The present invention provides novel methods for performing pulsed field mobility shift assays in microfluidic devices. In particular, the methods of the invention utilize differences between electrophoretic mobilities (e.g., as between reactants and products, especially in non-fluorogenic reactions) in order to separate the species and thus analyze the reaction.

High throughput mobility shift

The disclosure provides methods and materials for preparing a titania nanoparticle product. For example, titania nanoparticle products having desirable optical properties such as a desirable refractive index are prepared according to the methods provided herein.

Synthesis of metal oxide, titania nanoparticle product, and mixed metal oxide solutions

Traditional solar control applications rely on thin metal films to reflect EM radiation with wavelengths longer than that of the visible spectrum. Unfortunately such films also block radiation in cellular, GPS, and radio frequency bands. In one aspect, the disclosure provides a selectively-blocking filter that uses one or more optical filters tuned to a specific range(s) of wavelengths (e.g. for blocking IR radiation), while readily transmitting other wavelengths (e.g. both visible light and cellular/GPS signals). The filters can be manufactured on both flexible and rigid substrates.

Broadband solar control film

The invention provides materials and methods for forming coatings on substrates. The coatings are durable and resistant to damage from environmental, chemical, thermal, and/or radiative sources. In some embodiments, the coatings comprise bilayers of electrostatically charged materials. The bilayers are created by alternately applying solutions comprising water-soluble, electrostatically charged materials. Durability is imparted to the coatings by the formation of crosslinks that are formed within and between layers after deposition of the coatings.

Methods and materials for functional polyionic species and deposition thereof

The disclosure provides materials, apparatuses, and methods for making multilayer coatings with a high degree of efficiency and control. In some aspects, for example, coatings are described having multiple layers of nanoparticles and a polyelectrolyte, wherein the nanoparticles form tightly packed monolayers. The interface between monolayers may include polyelectrolyte material. One or more aspects of such monolayers and interfaces are controllable.

Methods, materials and apparatus for improving control and efficiency of layer-by-layer processes

The invention provides methods of controlling environmental conditions within a fluidic system, where such environmental conditions can affect the operation of the system in its desired function, and fluidic channels, devices, and systems that are used in practicing these methods. Such methods are generally directed to environmental control fluids, the movement of such fluids through these systems, and the interaction of these fluids with other components of the system, e.g., other fluids or solid components of the system.

Control of operation conditions within fluidic systems

Ligand compositions for use in preparing discrete coated nanostructures are provided, as well as the coated nanostructures themselves and devices incorporating same. Methods for post-deposition shell formation on a nanostructure, for reversibly modifying nanostructures, and for manipulating the electronic properties of nanostructures are also provided. The ligands and coated nanostructures of the present invention are particularly useful for close packed nanostructure compositions, which can have improved quantum confinement and/or reduced cross-talk between nanostructures. Ligands of the present invention are also useful for manipulating the electronic properties of nanostructure compositions (e.g., by modulating energy levels, creating internal bias fields, reducing charge transfer or leakage, etc.).

Compositions and methods for modulation of nanostructure energy levels

Siloxane polymer ligands for binding to quantum dots are provided. The polymers include a multiplicity of amine or carboxy binding ligands in combination with long-alkyl chains providing improved stability for the ligated quantum dots. The ligands and coated nanostructures of the present invention are useful for close packed nanostructure compositions, which can have improved quantum confinement and/or reduced cross-talk between nano structures.

Silicone ligands for stabilizing quantum dot films

Quantum-dot binding ligands with silsesquioxane moieties are provided. The quantum-dot binding ligands include a multiplicity of amine or carboxy binding ligands in combination with silsesquioxane moieties providing improved stability for the ligated quantum dots. The ligands and coated nanostructures of the present invention are useful for close packed nanostructure compositions, which can have improved quantum confinement and/or reduced cross-talk between nanostructures.

Polyhedral oligomeric silsesquioxane nanocrystal stabilization ligands

Methods for forming or patterning nanostructure arrays are provided. The methods involve formation of arrays on coatings comprising nanostructure association groups, formation of arrays in spin-on-dielectrics, solvent annealing after nanostructure deposition, patterning using resist, and/or use of devices that facilitate array formation. Related devices for forming nanostructure arrays are also provided, as are devices including nanostructure arrays (e.g., memory devices). Methods for protecting nanostructures from fusion during high temperature processing also are provided.

Methods and devices for forming nanostructure monolayers and devices including such monolayers

Matrixes doped with semiconductor nanocrystals are provided. In certain embodiments, the semiconductor nanocrystals have a size and composition such that they absorb or emit light at particular wavelengths. The nanocrystals can comprise ligands that allow for mixing with various matrix materials, including polymers, such that a minimal portion of light is scattered by the matrixes. The matrixes are optionally formed from the ligands. The matrixes of the present invention can be used as refractive index matching components, filters and antireflective coatings on optical devices and as down-converting layers. Processes for producing matrixes comprising semiconductor nanocrystals are also provided. Nanostructures having high quantum efficiency, small size, and/or a narrow size distribution are also described, as are methods of producing indium phosphide nanostructures and core-shell nanostructures with Group II-VI shells.

Functionalized matrices for dispersion of nanostructures

Growing community of inventors

Palo Alto, CA, United States of America

J Wallace Parce