Genzyme Corporation

Focal, Inc.

Andre Bieniarz

J Jeffrey Kablik

Dean M Pichon

Stephen Jack Herman

John M Kirwan

Thomas Bromander

David J Enscore

David J Nedder

Michael G Dumont

Glenn Kazo

John R Sousa

Albert H Linder

A modular system is described for construction of fluid applicators for open or endoscopic surgery from modular components. Lengths of tubing of various lengths, and devices to be carried by said tubing, are pre-fitted with standard adapters to mate with each other, thereby forming cannula sections and applicator sections. Interconnectors may also be provided, particularly for provision of articulation. The tubing is preferably rigid, but may also be either flexible or permanently bendable. A device can then be constructed by selection of a suitable set of tubing lengths, adapters and applicators. Devices customizable for particular uses can be created with minimal expense. The system is especially suitable for delivery of fluids to tissue in endoscopic or other minimally invasive surgical procedures. Delivery of fluids forming structure at a tissue site, especially as a hydrogel, is a preferred use of the devices.

Universal modular surgical applicator systems

A gas powered spraying device that can be used for single or multi-part reactive medical polymer compositions is provided. A fluid or one or more reactive solutions are sprayed independently at a tissue surface, and the spraying of each solution of multi-component embodiments is controlled by a separate valve. Each solution is provided with a separate spray outlet, and each spray outlet is surrounded by an annular sheath of flowing gas. Gas flow is provided at two or more flow levels, including a high level flow for active spraying and a low level bypass flow to remove drips and prevent clogging, which can improve device reliability. Gas pressure can be used to drive fluid to its spray outlet, as well as to spray the fluid from the outlet to the tissue surface.

Self-cleaning fluid delivery device for medical applications

Fluent agent delivery device

A device for testing the light power output of an optical system comprises a thermochromic element, a body element optionally providing collimation or other means of reproducible positioning, and optionally filters and attenuation. A preferred device fits onto the end of an optical power delivery system, and the thermochromic element changes color if the system output is above a defined threshold. An alternative device provides a flat target with a The device may be adapted to be sterilizable, and may be disposable. Optional means for ensuring that the light delivery system is operational during the measurement are provided.

Light source power tester

Premature Rupture of the Membranes (PROM) is a serious complication of pregnancy. PROM is treated by creation of a seal or barrier at the site of the rupture or in or near the cervix, thereby controlling the loss of amniotic fluid and preventing bacterial access. Instruments and techniques for application of sealing and barrier-forming materials at appropriate sites are described, as well as appropriate selection of materials and formation techniques. The instruments and techniques facilitate application of any fluent material to physiology associated with pregnancy and rendering the fluent material non fluent so as to form a barrier of seal.

Method of treatment for premature rupture of membranes in pregnancy (PROM)

Growing community of inventors

Tyngsboro, MA, United States of America

J Jeffrey Kablik