Honeywell International Inc.

Honeywell G.m.b.h.

J David Zook

Cleopatra Cabuz

Ulrich Bonne

James Allen Cox

David W Burns

Thomas R Ohnstein

Alex Gu

William R Herb

David W Deetz

Barrett E Cole

Steven J Eickhoff

Wei Yang

Aravind Padmanabhan

Teresa M Marta

Chunbo Zhang

Ernest Allen Satren

Juey H Lai

Robert P Ulmer

Eugen Loan Cabuz

David J Odde

Scott T Reimer

Michael L Rhodes

Daniel W Youngner

Adam Dewey McBrady

Carol M Ford

James F Detry

Charles T Sullivan

James B Starr

Scott A McPherson

Mona M Abdelrahman

Dan W Youngner

Barbara Goldenberg Barany

J Don Heaps

Barbara G Barany

Maurice L Hitchell, Deceased

An apparatus includes a plurality of islands each carrying multiple cantilevers. The apparatus also includes a fluidic network having a plurality of channels separating the islands. The channels are configured to provide fluid to the islands, and the fluid at least partially fills spaces between the cantilevers and the islands. Heat from the islands vaporizes the fluid filling the spaces between the cantilevers and the islands to transfer the heat away from the islands while driving the cantilevers into oscillation. The apparatus may also include a casing configured to surround the islands and the fluidic network to create a vapor chamber, where the vapor chamber is configured to retain the vaporized fluid. The islands and the fluidic network could be formed in a single substrate, or the islands could be separate and attached together by a binder located within the channels of the fluidic network.

Apparatus and method for thermal management using vapor chamber

Carbon nanotubes are formed on projections on a substrate. A metal, such as nickel is deposited on the substrate with optional platforms, and heated to form the projections. Carbon nanotubes are formed from the projections by heating in an ethylene, methane or CO atmosphere. A heat sensor is also formed proximate the carbon nanotubes. When exposed to IR radiation, the heat sensor detects changes in temperature representative of the IR radiation. In a gas sensor, a thermally isolated area, such as a pixel is formed on a substrate with an integrated heater. A pair of conductors each have a portion adjacent a portion of the other conductor with projections formed on the adjacent portions of the conductors. Multiple carbon nanotubes are formed between the conductors from one projection to another. IV characteristics of the nanotubes are measured between the conductors in the presence of a gas to be detected.

Carbon nanotube sensor

A method includes acquiring a chemical sample and modulating the chemical sample at a frequency greater than a drift frequency of a sensor. The method also includes determining at least one of a presence and a concentration of the analyte within the modulated chemical sample using the sensor. Modulating the chemical sample could include alternately absorbing at least some of the analyte into a sorbent material and releasing at least some of the analyte from the sorbent material. Modulating the chemical sample could also include heating the sorbent material, absorbing part of the analyte into the sorbent material, and passing a remaining portion of the analyte into the sensor. Modulating the chemical sample could further include stopping the heating of the sorbent material, releasing the part of the analyte from the sorbent material, and passing the sample with the released part of the analyte into the sensor.

Gas pulse generator for baseline drift correction and related system and method

A multiplexed set of light sources having outputs of light with various wavelengths which are combined into one beam. The beam may impinge a particle in a flow channel of a cytometer. The light leaving the flow channel may be sensed by a detector and the light distinguished according to wavelength.

Frequency-multiplexed detection of multiple wavelength light for flow cytometry

An optical system having a closed loop light path with a source for providing light in a direction parallel to the normal of an input to the light path. The light may be provided via a refracting mechanism to the input. The system may be a cavity ring-down sensor or some other optical device. The light path may be formed in a laser gyroscope type cavity. A light source may have a beam aligned to a spot, indicator or indicator or mark may be determined in accordance with parameters of the refracting mechanism and/or cavity. A fixture for holding the light source may be secured so that placement of the source in the fixture will automatically result in an aligned light source. Then the refracting mechanism may be inserted to further complete fabrication of the optical system.

Optical cavity system having an orthogonal input

A sampling system for detecting an analyte, comprising a diaphragm pump, a buffer chamber, a sensor head and intake port. The pump includes a chamber for receiving fluids via first and second ports. A buffer chamber is located at the second port for holding a quantity of air, and a sensor head is adapted to identify the presence of a desired analyte and produce a signal in response to the quantity identified. Preferably the diaphragm pump has a volume of gas per stroke capacity slightly larger than the volume of the sensor head such that the pump chamber has a greater volume than the buffer chamber and the buffer chamber has about the same volume as the sensor head. A sensor intake port intakes a sample potentially containing the analyte for contact with the sensor head upon operation of the diaphragm pump and out of the sensor head by jet-action caused by rapid movement of the diaphragm pump. A filter may be used for filtering air drawn through the pump chamber. The diaphragm pump may be either a single chamber pump or a multiple chamber diaphragm mesopump. In the purging mode, the system can also contain a pump for filling the system with clean air. When a mesopump is used, a single pumping channel can provide both AC and DC operation.

Meso sniffer: a device and method for active gas sampling using alternating flow

A frequency standard has a cell formed in a cavity of a substrate. The cell contains a metal alkali vapor. The substrate has an optical path that intersects the cell. A light source is supported by the substrate and supplies light through the first optical path to the cell, and a light detector is supported by the substrate and receives light through the second optical path from the cell. The sealed vapor-filled cell is surrounded by a vacuum cavity enclosure. Bridges between the cell and the substrate may be used to thermally isolate the cell in the cavity and allow closed loop temperature control of the cell.

MEMS frequency standard for devices such as atomic clock

A sensor device for detecting vibration, including a laser light, a first optical fiber for transmitting the laser light, an oscillator to receive the transmitted laser light and reflect the light as a frequency modulated light; a second optical fiber to transmit the frequency modulated light; and a frequency modulated discriminator for receiving the frequency modulated light from the second optical fiber and producing a signal responsive of vibration of the oscillator. In a preferred embodiment, the frequency modulated discriminator further includes a frequency meter for determining the average number of cycles per unit time to provide a second signal responsive of the temperature of the oscillator. The optical fibers may be a pair of different fibers positioned for transmitting the laser light and the frequency modulated light respectively, or the same fiber positioned for transmitting both the laser light and the frequency modulated light.

Fiber-optic vibration sensor based on frequency modulation of light-excited oscillators

A portable or wearable cytometer that can be used at remote locations, such as in the field or at home. The flow cytometer of the present invention may help improve the healthcare of many weak, sick or elderly people by providing early detection of infection. By detecting the infection early, the infection may be more readily treatable. In military applications, the portable cytometer of the present invention may help save lives by providing early detection of infection due to biological agents.

Portable flow cytometry

An optical detection system for flow cytometry that uses two or more light sources positioned laterally at different distances from the central axis of the flow stream for providing light through different parts of the flow stream. By using two or more light sources, the particle position can be detected, and the alignment and width of the core stream can be monitored and controlled. In addition, the velocity and size of the particles can be more accurately determined than when only a single light source is used.

Optical detection system for flow cytometry

A sampling system for detecting an analyte, comprising a diaphragm pump, a buffer chamber, a sensor head and intake port. The pump includes a chamber for receiving fluids via first and second ports. A buffer chamber is located at the second port for holding a quantity of air, and a sensor head is adapted to identify the presence of a desired analyte and produce a signal in response to the quantity identified. Preferably the diaphragm pump has a volume of gas per stroke capacity slightly larger than the volume of the sensor head such that the pump chamber has a greater volume than the buffer chamber and the buffer chamber has about the same volume as the sensor head. A sensor intake port intakes a sample potentially containing the analyte for contact with the sensor head upon operation of the diaphragm pump and out of the sensor head by jet-action caused by rapid movement of the diaphragm pump. A filter may be used for filtering air drawn through the pump chamber. The diaphragm pump may be either a single chamber pump or a multiple chamber diaphragm mesopump. In the purging mode, the system can also contain a pump for filling the system with cleaned air. When a mesopump is used, a single pumping channel can provide both AC and DC operation.

A fluid driving system for portable flow cytometers or other portable devices that accepts a less precise and less stable pressure source, and then adjusts the pressure in a closed-loop manner to maintain a constant, desired flow velocity. The fluid driving system may be used in portable or wearable cytometers for use in remote locations, such as at home or in the field.

Fluid driving system for flow cytometry

A sensor device for detecting vibration, including a light source for providing a laser light, a first optical fiber connected to the source for transmitting the laser light, an oscillator positioned to receive the transmitted laser light and adapted to reflect the light as a frequency modulated light; a second optical fiber positioned to capture the frequency modulated light to transmit the frequency modulated light; and a frequency modulated discriminator for receiving the frequency modulated light from the second optical fiber and producing a signal responsive of vibration of the oscillator. In a preferred embodiment, the frequency modulated discriminator further includes a frequency meter for determining the average number of cycles per unit time to provide a second signal responsive of the temperature of the oscillator. The optical fibers may be a pair of different fibers positioned for transmitting the laser light and the frequency modulated light respectively, or the same fiber positioned for transmitting both the laser light and the frequency modulated light. In this latter embodiment, the device further includes a beam splitter to direct the frequency modulated light to the discriminator. The preferred oscillator includes a microchip having a microbeam mounted on a thin silicon cantilever such that deflection of the beam perpendicular to the plane of the microchip changes the tension in the microbeam to change its resonant frequency. Also preferred is a microbeam including a thin metal deposit to create a bimorph structure.

A diaphragm pump, which is preferably electrostatically actuated, but which may be activated by other forces such as electromagnetic or piezoelectric actuation. The pump is formed by a pump body having a pump chamber formed therein. First and second diaphragms each having a set of valve holes in the diaphragm surface thereof are mounted in the chamber. Also provided are at least one inlet and at least one outlet port for communication with the pump chamber. The ports are positioned for sealing contact with the diaphragms at points that are not aligned with the holes in the diaphragms. A driver electrostatically actuates the diaphragms to cause diaphragm movement to a plurality of diaphragm positions to control flow of fluid through the pump. The first position is when the diaphragms are spaced from one another and from the ports to permit flow of fluid through the pump chamber. The second position is when the diaphragms are in diaphragm surface contact with the sets of holes mutually nonaligned to form a seal between the diaphragms. The third position is when a diaphragm is in diaphragm surface contact with the ports to form the sealing contact.

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Golden Valley, MN, United States of America

J David Zook