Schering Corporation

J Allan Waitz

Joseph A Marquez

Mahesh G Patel

Ann C Horan

Imbi Truumees

Walter Reiblein

An-Dien Nguyen

Linh Nguyen

Bong K Lee

Mandeep Sahani

Apparatus(es)/method(s) relating generally to remotely administering a medication is/are disclosed. In one such method, a drug delivery device is obtained. The drug delivery device has: at least one reservoir in fluid communication with a needle; at least one actuator to drive a fluid within a respective at least one reservoir to the needle; a microcontroller to control operation of the at least one actuator; and a dosage control loop configured for communication with the microcontroller and a hemoglobin sensor. A dosage provided by the drug delivery device is automatically adjusted responsive to hemoglobin count sensed by the hemoglobin sensor for transdermal administration of medication for management of chronic kidney disease.

Wearable drug delivery device for disease management and system therefor with artificial intelligence

The novel triacetylenic dioxolone antifungal compound of this invention is isolated from the EV-22 complex of this invention which is elaborated by the microorganism Microbispora sp. SCC 1438, ATCC 53620.

ATCC 53620 production of a triacetylenic dioxolone with Microbispora sp.

Antifungal triacetylenic dioxolone from Microbispora sp. SCC 1438, ATCC

The Antiboitic AR-5 complex is elaborated by a novel species of the Micromonospora; namely, Micromonospora polytrota. The microorganism also elaborates a number of minor components including the gentamicin complex and a complex of anthroquinone antibiotics.

Process of producing antibiotic AR-5 complex

The AR-5-3 Complex consisting of four macrolide antibiotics is elaborated by a mutant strain of Micromonospora polytrota. The antibiotics exhibit substantial activity against gram positive bacteria in vitro and in vivo.

Macrolide antibiotic complex

The Antibiotic AR-5 complex is elaborated by a novel species of the Micromonospora; namely, Micromonospora polytrota. The microorganism also elaborates a number of minor components including the gentamicin complex and a complex of gentamicin antibiotics.

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Portola Valley, CA, United States of America

J Allan Waitz