Sanwa Kagaku Kenkyusho Co., Ltd.

Izumi Gotoh

Hiroki Nagano

Mitsuaki Takeuchi

Toshiyuki Miyazawa

Daisuke Kurumazuka

Satoko Harada

Toru Izuchi

Morio Okabe

Yuka Kuno

Yasushi Ohsawa

Yurie Yamada

Yukiyasu Asano

Naoki Takahashi

Keita Sakai

Hiroki Fujieda

Hiroyo Kataoka

Nobuyoshi Kasugai

Katsunori Kitamoto

A compound having a V2 receptor agonistic activity is provided. Providing a pharmaceutical composition which contains, as an active ingredient, a compound represented by general formula (I) described below: [Ris formula described below: (A is a lower alkylene group which may be substituted with lower alkyl group; Ris a hydrogen atom; Ris a hydroxyl group, an aromatic heterocyclic group which may be substituted with lower alkyl group, carbamoyl group); Ris a hydrogen atom or lower alkyl group; Ris lower alkyl group which may be substituted with 1-3 fluorine atoms, or halogen atom; Ris a five-membered aromatic monocyclic heterocyclic group, five-membered non-aromatic monocyclic heterocyclic group, (provided each heterocyclic groups contain at least one nitrogen atom and may be substituted with a lower alkyl group); and Ris a lower alkyl group, halogen atom], or pharmacologically acceptable salt thereof.

Benzoazepine derivative and medical use thereof

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Kuwana, Japan

Izumi Gotoh