Medspray Xmems B.v.

Nanomi B.v.

Iwan Rutger Heskamp

Wietze Nijdam

Jeroen Mathijn Wissink

Cornelis Johannes Maria Van Rijn

Wilhelmus Petrus Johannes De Kruijf

Gerrit Jan Veldhuis

Christiaan Haldir Goeting

Marc Herman Padberg

An inhaler with a mixing channel () for producing an aerosol to be inhaled includes an outlet () at one end that can be inserted in the mouth of a person in order to inhale the aerosol that is produced; at least one inlet () at its other end for drawing air into the mixing channel (); and at least one injection zone () that lies between the inlet () and the outlet () and forms part of the channel wall. The injection zone () has at least one nozzle orifice () for supplying a liquid, especially a liquid drug, wherein the inner surface of the injection zone () is largely flush at least with that portion of the mean surface curvature () of the inner surface of the channel wall () that is adjacent to it on the inlet end. A possible height difference () between the inner surface of the injection zone () and that portion of the mean surface curvature () of the inner surface of the channel wall () that is adjacent to it is less than 1 mm or at most 100 &#x3bc;m or at most 20 &#x3bc;m.

Inhaler with a mixing channel for producing an aerosol to be inhaled

A method of manufacturing an atomizing body for an atomizing device includes the steps of providing a support element having a first layer on a first surface of the support element and a second layer on a second surface of the support element, the first layer including a first perforated membrane and the second layer including a process orifice, etching a cavity through the support element, the cavity forming a fluid connection from the process orifice to the perforated membrane, by providing etching substance to the process orifice. The atomizing body as obtained may advantageously be applied in an atomizing device or an inhaler.

Atomising body, atomising device, inhaler, manufacturing method of manufacturing an atomising body and assembly method for assembling an atomising device

An atomizing device, includes an atomizing body () with an inlet () for receiving a fluid under increased pressure, and with at least one set of outflow ports () for allowing the fluid to escape on a delivery side with forming of a vapor. Imaginary central axes of the outflow ports directed in a flow direction herein enclose a mutual angle (&#x3b1;) in order to intersect each other at an intersection (S). The atomizing body includes a roof () and a bottom (which extend over at least a first distance (d) beyond the set of outflow ports () and bound a vaporizing space () on either side. The intersection (S) of the imaginary central axes of the outflow ports lies at a second distance (d) from the set of outflow ports, wherein the second distance (d) is greater than the first distance (d) and extends beyond the vaporizing space.

Atomising device, atomising body and method of manufacturing the same

A device for generating microspheres from a fluid includes an injection plate with at least one defined injection channel having on an inlet side an inflow opening for receiving the fluid and on an outlet side an outflow opening for delivering microspheres formed from the fluid. The device includes feed elements for carrying fluid through the injection channel and is in open communication, on a side wall thereof, with at least one secondary channel at least at the position of a break-up point where at least during operation a flow of fluid in the injection channel breaks up into separate parts. The secondary channel includes in use an auxiliary fluid at least at the position of a break-up point.

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Enschede, Netherlands

Iwan Rutger Heskamp