Drm. Dr. Muller Ag

Drm, Dr. Mueller Ag

Polytag Technology Sa

Ivo Schumacher

Hans Muller

Werner Stahl

Frank Hilbrig

Ruth Freitag

Walter Stocker

Patrick Mueller

Patrick A Muller

The method of making the clear cell lysate containing plasmid DNA from a biomass obtained in a cell culture process includes filtering the biomass obtained in the cell culture process with a filter medium in the presence of diatomaceous earth acting as a filtering agent to form a filter cake containing the biomass and the filter medium, then thermally digesting the biomass in the filter cake to form a cell lysate containing the plasmid DNA and filtering the cell lysate to form a clear filtrate. The clear filtrate contains the plasmid DNA and has a clarity characterized by an ODof at maximum 0.05 U/cm.

Method for treating biomass for producing cell lysate containing plasmid DNA

The multiple-tube filter proposed consists of at least one perforated filter element (15) whose outside surface has grooves (2) in a spiral round it, the surface between the grooves (2) preferably curving outwards in a circular arc.

Candle filter element

A candle filter element adapted to be located inside a pressure vessel and fixed in a hanging position to a collector tube for aseptic and/or sterile filtration of liquids, has a coupling with conical upper coupling part and a conical lower coupling part, with the conical upper coupling part provided with a rinsing opening and a pair of cams.

Candle filter elements and method for fixing same in a pressure vessel

Filter element and method of filtration

A filter candle element which is mounted in depending manner in a pressure container has a support body and a filter tissue which covers the support body and has at least one impermeable portion so as to prevent the depositing of a continuous filter cake. Through provision of a plurality of impermeable portions, the filter cake is divided into several pieces which do not obstruct their removal. The impermeable portions are obtained by spraying of synthetic material onto the filter tissue. These filter candle elements are especially suitable for alluvial filters of large dimensions.

Filter candle and method for producing the same

An arrangement for fastening filter candles and filter apparatus provided therewith includes a collecting pipe which is composed of several T-shaped pipe pieces. Each of the pipe pieces has a substantially horizontal portion and extending therefrom a second portion which has a free end part provided with a groove. Each of the filter candles has an upper part provided with a flange portion which is engageable into the groove to obtain a tight attachment of the filter candle to the collecting pipe.

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Jona, Switzerland

Ivo Schumacher