Glaxosmithkline Istrazivacki Centar Zagreb D.o.o.

Ivica Malnar

Milan Mesic

Mladen Mercep

Stribor Markovic

Boska Hrvacic

Ivaylo Jivkov Elenkov

Anita Filipovic

Lidija Simicic

Andreja Cempuh Klonkay

The invention relates to novel compounds of the formula (I) including all their tautomers, to pharmaceutically acceptable salts and solvates thereof, to processes and reactive intermediates for the preparation thereof, and to processes and reactive intermediates for the preparation of the compounds of the formula (II) including all their stereoisomers and tautomers to the use of the compounds of the formula (II) as suitable precursors for the preparation of the compounds of the formula (I) as well as to use of the compounds of the formula (I) and of the compounds of the formula (II) as therapeutically active agents in the prophylaxis and treatment of asthma and other inflammatory diesases and conditions in humans.

Substituted furochromenes, preparation thereof and their antiinflammatory action

The present invention relates to novel compounds of the formula (I) including all stereoisomers and tautomers thereof, to the pharmaceutically acceptable salts and solvates thereof, to the processes and reactive intermediates for their preparation and to their use in the prophylaxis and treatment of asthma and other inflammatory diseases and/or conditions in humans.

Substituted furochromene compounds of antiinflammatory action

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Gerovo, Croatia

Ivica Malnar