Koninklijke Philips Corporation N.V.

The University of Texas System

Ivan Pedrosa

Peter Boernert

Mariya Ivanova Doneva

Ivan Dimitrov

Nadine Gdaniec

Ananth Madhuranthakam

A method of operating a magnetic resonance imaging system () with regard to acquiring multiple-phase dynamic contrast-enhanced magnetic resonance images, the method comprising steps of acquiring () a first set of magnetic resonance image data (x) prior to administering a contrast agent to the subject of interest (), by employing a water/fat magnetic resonance signal separation technique, determining () a first image of the spatial distribution of fat (I) of at least the portion of the subject of interest (), acquiring () at least a second set of magnetic resonance image data (x) of at least the portion of the subject of interest () after administering the contrast agent to the subject of interest (), by employing a water/fat magnetic resonance signal separation technique, determining () at least a second image of the spatial distribution of fat (I) of at least the portion of the subject of interest (), applying () an image registration method to the second image of the spatial distribution of fat (I) with reference to the first image of the spatial distribution of fat (I) for correcting a potential motion of the subject of interest (); and a magnetic resonance imaging system () having a control unit () that is configured to carry out steps (-) of such a method; and a software module () for carrying out such a method, wherein the method steps (-) to be conducted are converted into a program code that is implementable in a memory unit () and is executable by a processor unit () of the magnetic resonance imaging system ().

Method of improved multiple-phase dynamic contrast-enhanced magnetic resonance imaging with motion correction using water/fat signal separation

A magnetic resonance imaging (MRI) system (), the system includes at least one controller () which performs a modified rotated slab excitation (mROSE) sequence for volume selection to exclude portions of a subject under exam which are within the scanning volume and outside of a field-of-view (FOV) so as to reduce foldover artifacts which originate from the excluded portions of the subject under exam, where the mROSE sequence performs volume excitation based upon either optimized symmetrical, minimum-phase, or stretched minimum-phase radio-frequency (RF) pulses in a sagittal plane and encodes the scanning volume in a coronal plane. The controller also performs a chemical-shift sequence including a modified DIXON (mDIXON) sequence for substantially uniform fat/water separation within a FOV which lies within the scanning volume; and/or acquires echo information for reconstructing at least a part of an image.

MRI using a modified DIXON sequence with reduction of fold-over artifacts

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Eindhoven, Netherlands

Ivan Pedrosa