Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Université Paris Descartes

Université Paris Diderot-Paris 7

Université Paris—sud

Assistance Publique - Hopitaux De Paris (Aphp)

Foundation Imagine

Ivan Cruz-Moura

Olivier Hermine

Etienne Paubelle

Thiago Trovati Maciel

Florence Zylbersztejn

Michael Dussiot

The present invention concerns a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for simultaneous or sequential use in the treatment of a drug resistant cancer and/or in prevention of tumor relapse in a patient suffering from cancer. The present invention also relates to a combination of (i) a DNA methylation inhibitor, and (ii) a Vitamin D receptor agonist, for increasing, restoring or enhancing sensitivity of a patient suffering from cancer to a chemotherapeutic drug in a patient suffering from cancer.

Composition comprising a combination of DNA methylation inhibitor and a vitamin D receptor agonist for the treatment of drug resistant cancer or for the prevention of tumor relapse

Growing community of inventors

Paris, France

Ivan Cruz-Moura