Mitsubishi Kasei Corporation

Agro-Kanesho Co., Ltd.

Itaru Okada

Toshiki Fukuchi

Shuko Okui

Yoji Takahashi

Ryo Aizawa

Shigeru Suzuki

Masahiro Hatamoto

Tetsuo Nakajima

Mabuko Yamaura

Mana Nishimata

The present invention provides a method of producing a 2-aminonicotinic acid benzyl ester derivative at a high yield and with a high purity. By reacting a benzyl halide derivative with a 2-aminonicotinic acid derivative in a polar solvent in the presence of a prescribed base, it is possible to obtain a 2-aminonicotinic acid benzyl ester derivative at a high yield and with a high purity.

Method of producing 2-aminonicotinic acid benzyl ester derivatives

The present invention provides a bactericide containing a 2-aminonicotinic acid ester derivative as an active ingredient. The active ingredient is represented by the following formula [I]: (wherein, Rrepresents a hydrogen atom or a C-Calkyl group, Rrepresents a hydrogen atom or a C-Calkyl group, Rand Rmay be combined together to form an alkylene chain, Rrepresents a hydrogen atom or a C-Calkyl group, Rrepresents a hydrogen atom, a cyano group or a C-Calkyl group, Rand Rindependently represent a hydrogen atom, a halogen atom, a C-Calkyl group, a C-Calkoxy group, a C-Calkylthio group, a C-Calkylsulfinyl group, a C-Calkylsulfonyl group, a nitro group, a cyano group, a C-Chaloalkyl group, a C-Chaloalkoxy group or a C-Chaloalkylthio group, A and B independently represent a methine (CH) group or a nitrogen atom).

2-aminonicotinic acid ester derivative and bactericide containing same as active ingredient

Novel pyrazole amide and an insecticidal and miticidal composition containing the pyrazole amide as an active ingredient are described. The pyrazole amide according to the present invention shows excellent insecticidal and miticidal activities.

Pyrazole amides and insecticide and miticide containing them as active

Disclosed herein are pyrazole derivatives which are represented by the following formula (I): ##STR1## wherein R.sup.1 represents a C.sub.1 -C.sub.4 alkyl group or a benzyl group; R.sup.2 represents a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group; X represents a hydrogen atom, a halogen atom or a C.sub.1 -C.sub.4 alkyl group; R.sup.2 may combine with X to form ##STR2## wherein R.sup.5 represents a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group; R.sup.3 represents a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group; R.sup.4 s independently represent a hydrogen atom, a halogen atom, a C.sub.1 -C.sub.5 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a C.sub.1 -C.sub.4 alkylthio group, a trifluoromethyl group, a C.sub.1 -C.sub.4 haloalkoxy group, a phenyl group, an alkyl-substituted phenyl group or ##STR3## wherein Y represents an oxygen atom or a sulfur atom, R.sup.6 s independently represent a hydrogen atom, a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a halogen atom, a nitro group, a cyano group or a trifluoromethyl group and n represents 1 or 2, adjacent R.sup.4 s being able to combine together to form ##STR4## wherein R.sup.7 represents a hydrogen atom or a methyl group; l represents 0 or 1; and m represents 1, 2, or 3. The pyrazole derivatives of the formula (I) show a high activity suitable for active ingredient of insecticidal and miticidal composition as well as fungicidal composition.

Pyrazole derivatives and insecticidal fungicidal and miticidal

A novel pyrazole derivative and an insecticidal or miticidal composition containing the derivative as the effective ingredient are disclosed. The pyrazole derivative of the present invention has an excellent controlling effect also against harmful insects and mites exhibiting resistance to conventional insecticides and does not disturb the ecosystem since it is less toxic and less residual.

Growing community of inventors

Kanagawa, Japan

Itaru Okada