Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

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Gyogyszer- Es Vegyeszeti Termekek Gyara Rt.

Istvan Tibor Toth

Lajos Szabo

Csaba Szantay

Sandor Virag

Geza Toth

Erzsebet Kanyo

Agoston David

Laszlo Toke

Istvan Elekes

Sandor Elek

Istvan Polgari

Andrea Maderspach

Jozsef Borsy

Pal Bite

Gyorgy Magyar

Eszter Diszler

Gabor Kovacs

Gyula Sebestyen

Jozsef Gaal

Jeno Marton

Laszlo Simandi

Gyorgy Somogyi

Gabor Besenyei

Gyula Szilagyi

Ferenc Nagy

Tibor Montay

Laszlo Harsing

Istvan Szita

Csaba Szantai

Szilveszter Vizi

Peter Viski

Gyula Pazmandi

Gyorgy Paszthy

Ilona Szigeti Nee Kiss

The invention relates to novel racemic or optically active berban derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 represent independently from the other a hydroxyl, straight or branched chain alkoxy group 1 to 6 carbon atoms or R.sup.1 and R.sup.2 together represent a C.sub.1-3 alkylenedioxy group;

Berban derivatives as .alpha..sub.2 -adrenergic antagonists

The invention relates to a new process for preparing known thiolcarbamate esters of the general formula (I) ##STR1## wherein R.sup.1 and R.sup.2 stand independently for hydrogen or a straight or branched chain alkyl group containing 1 to 6 carbon atoms or an alkenyl group containing 2 to 6 atoms, or an alkyl group containing 1 to 6 or an alkenyl group containing 2 to 6 carbon atoms and mono- or polysubstituted by halogen, oxygen, sulphur and/or nitrogen; or

Process for preparing esters of thiolcarbamic acids

An antiphlogistic compound of the formula (I) ##STR1## or a pharmaceutically effective salt thereof wherein R.sup.1 and R.sup.2 are hydrogen or C.sub.1-4 alkoxy or together form a methylenedioxy group;

Benzo(a)quinolizidine derivatives

2-oxo-3-(.beta.-cyanoethyl)-9,10-methylenedioxy-1,2,3,4,6,7-hexahydro-11bH- benzo(a)quinolizidine (SC-118) especially and the corresponding 9,10-diethoxy compound are superior antiphlogistics which are used in effective amounts in antiphlogistic therapy.

Antiphlogistic method of treatment

There are provided new compounds of the formula I ##STR1## wherein both R.sup.1 moieties stand for an alkyl group having 1 to 4 carbon atoms or form together a methylene bridge,

1,2,3,4,6,7-Hexahydro-11B.alpha.H-benzo[a]quinolizine-derivatives

A fungicidal composition contains as an active ingredient a compound of the formula ##STR1## wherein R.sub.1 is hydrogen or a carbamoyl group, R.sub.2, R.sub.3 and R.sub.5 are hydrogen or C.sub.1 - C.sub.7 alkyl.

2-(5-Nitro-furfurylidene)-amino-benzimidoles and fungicidal compositions

2-phenoxy-, 2-phenylthio-, and 2-phenylamino-alkyl-2-oxazolines suitable for pharmaceutical use as hypolipemic and hypocholestric agents are disclosed.

2-Phenoxy and 2-phenylthio and 2-phenylamino-alkyl-2-oxazolines

A process for the preparation of a compound of the formula I or a salt thereof ##STR1## wherein R.sup.1 and R.sup.2 each represent hydrogen or a C.sub.1-4 alkoxy group, or together form a methylenedioxy group;

Process for the preparation of benzo(a)quinolizidine derivatives

A process for the preparation of a compound of the formula: ##STR1## wherein R.sup.1 is alkyl, alkyl substituted by halogen, alkyl substituted by alkoxy, aryl, aryl substituted by halogen, aryl substituted by alkyl, aryl substituted by alkoxy, aralkyl, aralkyl substituted by alkoxy, cycloalkyl, cycloalkyl substituted by halogen, cycloalkyl substituted by alkyl or cycloalkyl substituted by alkoxy, and

Process for the preparation of carbamate derivatives

A fungicidal and fungistatic composition contains, as an effective ingredient, a compound of the formula ##STR1## and antifungal and pharmaceutically effective salts thereof wherein R.sup.1 is H and R.sup.5 is a group with the formula ##STR2## in which R.sup.2 and R.sup.3 are each hydrogen or C.sub.1 -C.sub.6 alkyl.

Benzimidazole derivatives and fungicidal composition and method

This invention relates to compounds of the formula ##SPC1## Wherein

2-Oxazoline derivatives

Antifungal substituted carbamoyl benzimidazole compounds of the formula ##SPC1## Wherein R.sup.2 and R.sup.3 are hydrogen or alkyl and R.sup.4 is aryl, alkyl or cycloalkyl. The compounds can be used as seed treatment.

Substituted carbamoyl benzimidazole derivatives with antifungal

Growing community of inventors

Budapest, Hungary

Istvan Tibor Toth