Richter Gedeon Vegyeszeti Gyar Rt

Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Egyt Gyogyszervegyeszeti Gyar

Egis Gyogyszergyar

Gyogyszerkutato Intezet

Gyogyszer- Es Vegyeszeti Termekek Gyara Rt.

Istvan Polgari

Istvan Elekes

Sandor Elek

Endre Kasztreiner

Laszlo Tardos

Gyorgy Cseh

Laszlo Jaszlits

Edit Kosa

Geza Szilagyi

Ferenc Andrasi

Istvan Tibor Toth

Peter Matyus

Jozsef Borsi

Andrea Maderspach

Judit Kosary

Jozsef Borsy

Agnes Kenessey

Zsuzsa Huszti

Pal Bite

Pal Tolnay

Gyorgy Magyar

Eszter Diszler

Imre Moravcsik

Sandor Bajusz

Tamas Hamori

Pal Berzsenyi

Jeno Korosi

Tibor Lang

Endre Csanyi

Gyorgy Rabloczky

Gabor Zolyomi

Erzsebet Mago Nee Karacsony

Maria Kuhar Nee Kurthy

Geza Schneider

Lajos Farkas

Zsuzsanna Lang Nee Rihmer

Ildiko Kiraly

Arpad Lazar

Judit Sarossy Nee Kincsesy

Szilagyi Geza

Andras Divald

Krisztina Heltai

Ilona Kovacs, Nee Szabo

This invention relates to new 1-(hydroxystyryl)-5H-2,3-benzodiazepine derivatives of the general formula (I) and to a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same, ##STR1## wherein R stands for a hydrogen or halogen atom, or a C.sub.1-4 alkoxy group,

1-(hydroxystyrl)-5H-2,3-benzodiazepine derivatives, and pharmaceutical

4-[(3,4-Dialkoxyphenyl)alkyl]-2-imidazolidinone derivatives having the formula I ##STR1## wherein R.sup.1 stands for a cycloalkyl group containing from 3 to 6 carbon atoms or benzyl group;

Anorexigenic 4-[(3,4-dialkoxyphenyl)alkyl]-2-imidazolidinone derivatives

Pyridazinylhydrazones capable of lowering blood pressure have the formula ##STR1## wherein R.sup.1 is hydrogen, chlorine, alkyl having from 1 to 4 carbon atoms, methoxy, hydroxyl, carbamoyl or cyano;

Novel pyridazinylhydrazones and method of administering same

Pyridazinylhydrazones capable of lowering blood pressure having the formula ##STR1## wherein R.sup.1 is hydrogen, chlorine, alkyl having from 1 to 4 carbon atoms, methoxy, hydroxyl, carbamoyl or cyano;

Morpholino pyridazinylhydrazones

3-(1-Pyrazolyl)-pyridazine derivatives of the formula I, or pharmaceutically acceptable acid addition salts thereof, which decrease high blood pressure and inhibit catabolism or prostaglandins, ##STR1## wherein R.sup.1 is hydrogen or C.sub.1-4 alkyl,

3-(1-Pyrazolyl)-pyridazine derivatives

The invention relates to compounds of general formula ##STR1## wherein R.sup.1 stands for a hydrogen atom or a C.sub.1-6 alkyl-, a C.sub.2-4 hydroxyalkyl, a C.sub.3-6 cycloalkyl or a phenyl group,

3-(1-Pyrazolyl)-pyridazine derivatives and hypotensive compositions

2-phenoxy-, 2-phenylthio-, and 2-phenylamino-alkyl-2-oxazolines suitable for pharmaceutical use as hypolipemic and hypocholestric agents are disclosed.

2-Phenoxy and 2-phenylthio and 2-phenylamino-alkyl-2-oxazolines

The invention relates to a novel compound of the formula ##STR1## and the pharmaceuticlly acceptable acid addition salts thereof, wherein R stands for a hydrogen atom or methyl group, x y designates a ##STR2## Q is a hydrogen atom or a benzyloxycarbonyl- or N-tert.-butyloxycarbonyl protective group, and R.sub.1 is the side chain of a natural .alpha.-amino acid selected from the group consisting of Arg--, Tryp-13 , Phe--, Ser--, Leu--, Val--, Meth--, Tyr--, His-- or Prol---side-chain. The compounds according to the invention possess antiserotonin and hypotensive effects and act upon the central nervous system.

Compounds of ergolene and ergoline structure and method for the

This invention relates to compounds of the formula ##SPC1## Wherein

2-Oxazoline derivatives

New acylated 2-aminothiazole derivatives of the general formula (I), ##SPC1## wherein

Acylated 2-aminothiazole derivatives

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Budapest, Hungary

Istvan Polgari