Richter Gedeon Vegyeszeti Gyar Rt

Istvan Hegedus

Csaba Szantay

Janos Kreidl

Andras Nemes

Bela Stefko

Laszlo Czibula

Gabor Blasko

Erik Bogsch

Andras Vedres

Eva Werkne Papp

Tamas Mester

Denes Mathe

Ida Deutschne Juhasz

Gyorgy Kalaus

Kalman Harsanyi

Maria Farkas Nee Kirjak

Katalin Nogradi

Laszlo Dobay

Istvan Borza

Janos Sapi

Judit M Meszaros Nee Brill

Ida Deutsch Nee Juhasz

Judit Nagyne Bagdy

Zsuzsanna Aracs Nee Tischler

Bela Benke

Ida Nee Deutsch

Kalmam Gaf

Katalin Horvath Nee Berki

Juidit Nagyne Bagdy

Jánosné´ Kreidl Née Regina Hegedus, Legal Representative

Mihaly Szegedi

Maria Nee Farkas

Adrien Szuchovszky Nee Gergely

Jenone Farkas

Adrien Szuchovszky, Nee Gergely

Agnes Piller

Lajos Szaho

Kalman Graf

A new process is disclosed for the synthesis of fluconazole monohydrate and for crystal modifications of fluconazole which comprises the step of 

Process for preparing monohydrate and crystal modifications of fluconazole

N-benzylpiperidine and tetrahydropyridine derivatives

Substituted propane-2-OL derivatives

New intermediate compounds are disclosed of the formula I, ##STR1## wherein R.sub.1 and R.sub.2 are independently alkyl having 1 to 4 carbon atoms, or acid-addition salts thereof of formula Ib, ##STR2## wherein X represents an acid residue, and a process for the preparation of the intermediate compounds.

Racemic and optically active octahydro-indolo(2,3-a) tetrahydropyranyl

The invention relates to a new process for preparing 6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine of the formula (I), ##STR1## which comprises reacting a pyrimidine derivative of the general formula (II), ##STR2## wherein R.sub.1 stantds for hydrogen or a ##STR3## group, wherein R means a C.sub.1-6 alkyl group or an aryl group optionally substituted by halogen;

Preparation of

A pyrimidine derivative of the formulae (Ia), (Ib) and (Ic), ##STR1## wherein R stands for an alkyl group group with 1 to 6 carbon atoms or an aryl group optionally substituted by halogen atom; and

Pyrimidine derivatives and process preparing the same

Growing community of inventors

Budapest, Hungary

Istvan Hegedus