Richter Gedeon Vegyeszeti Gyar Rt

Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Istvan Bartho

Gyorgy Santha

Laszlo Cseke

Karoly Zalai

Laszlo Kozma

Bela Makadi

Mihaly Kaszas

Gabriella Kordik

Gyula Beszedics

Sandor Kovats

Sandor Pusztai

Miklos Feder

Karoly Gergely

Jozsef Szejtli

Agnes Stadler Nee Szoke

Eva Udvardy Nagy Nee Cserey Pechany

Maria Trinn

Gabor Hantos

Marta Balazs Nee Czurda

Ilona Habon

Zsuzsa Vida

A mixing device, especially for a fermenter, capable of dispersing gas in a broth therein, in which a number of propeller mixers are provided on a vertically extending shaft. The lower propeller mixer is a gas dispersing mixer having a hollow hub and open channels on the blades extending from this hub and tapering outwardly. At least one intermediate propeller mixer has some blades shorter than others and of reverse flow direction, some blades having baffle bars on trail edges thereof. The upper propeller mixer has the longer blades without channels and flow modifying elements.

Complex mixing device for dispersion of gases in liquid

Complex mixing system with stages consisting of propeller mixers of high diameter ratio, where the blades are provided with flow modifying elements, whereby the energy proportions spent on dispersion of the amount of gas injected into the reactor, homogenization of the multi-phase mixtures, suspension of solid particles, etc. and the properties corresponding to the rheological properties of the gas-liquid mixtures and to the special requirements of the processes can be ensured even in extreme cases. Open channels (5) opposite to the direction of rotation are on the blades (4) of the dispersing stage (2a) of the propeller mixers (2) fixed to a common shaft, where the channels (5) are interconnected with gas inlet (7). The angle of incidence of a certain part of the blades (4) of mixing stages (2b, 2d) used for homogenization and suspension is of opposite direction and the length is shorter and/or the angle of incidence is smaller than those of the other blades. Baffle bars (8) are on the trailing end of the blades on a certain part (2c) of the propeller mixers used similarly for homogenization and suspension, and/or auxiliary blades (12) at an angle of max. 20.degree. to the blade wings are arranged above or below the trailing end of the blades (FIG. 1 and 6).

Complex mixer for dispersion of gases in liquid

Microbiological conversions of cyclodextrins are intensified by adding to the reaction mixture 0.2 to 3 moles of .alpha.-, .beta.- or .gamma.-cyclodextrin or an optical mixture thereof pro mole of the steroid substrate, before, at the beginning or during the conversion. The cyclodextrin if desired, can be removed after the reaction. In this way the reaction velocity can be increased, the reaction time is reduced, the substrate concentration in the solution, i.e. its solubility is increased or the so called product inhibition may be avoided. In certain cases of more alternatives the desired reaction can be catalyzed and in this manner the selectivity is increased.

Process for the intensification of microbiological conversions of

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Budapest, Hungary

Istvan Bartho