Smithkline Beecham Corporation

Smithkline Beechman Corporation

Israel Simon Gloger

Deirdre Mary Bernadette Hickey

Colin Houston MacPhee

Christopher Donald Southan

David Graham Tew

Simon Quentyn John Rice

Geoffrey Mark Prouse Lawrence

Conrad Gerald Chapman

Joanne Rachel Evans

Hugh Jonathan Herdon

Anthony M Brown

William Cairns

Tania Tamson Testa

Jonathan Alexander Terrett

Trudy Rachel Doe

Simon Quentyn Rice

Geoffrey Mark Lawrence

Stephen A Hughes

The enzyme Lp-PLAin purified form, an isolated nucleic acid molecule encoding Lp-PLA, the use of an inhibitor of the enzyme Lp-PLAin therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.

Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy

The enzyme Lp-PLAin purified form, an isolated nucleic acid molecule encoding Lp-PLA, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.

The SC6 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing SC6 polypeptides and polynucleotides in therapy, and diagnostic assays for such.

Neurotransmitter transporter SC6

Tubby 2 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Tubby 2 polypeptides and polynucleotides in the design of protocols for the treatment of diabetes, obesity, and atherosclerosis, among others, and diagnostic assays for such conditions.

Tubby 2 polypeptides

The enzyme Lp-PLA,in purified form, an isolated nucleic acid molecule encoding Lp-PLA,, the use of an inhibitor of the enzyme Lp-PLA,in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.

The enzyme Lp-PLA.sub.2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA.sub.2, the use of an inhibitor of the enzyme Lp-PLA.sub.2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.

Lipoprotein associated phospholipase A2, inhibitors thereof and use of

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London, United Kingdom

Israel Simon Gloger