Ramot University Authority for Applied Research and Industrial Development Limited

Opticul Diagnostics Ltd.

Israel Gannot

Jacob Dror

Nathan Croitoru

Gallya Gannot

Dror Lederman

Reuben Dahan

Hassan Moinuddin

Isaac Kaplan

A spectroscopic method for spectroscopic detection and identification of bacteria in culture is disclosed. The method incorporates construction of at least one data set, which may be a spectrum, interference pattern, or scattering pattern, from a cultured sample suspected of containing said bacteria. The data set is corrected for the presence of water in the sample, spectral features are extracted using a principal components analysis, and the features are classified using a learning algorithm. In some embodiments of the invention, for example, to differentiate MRSA from MSSA, a multimodal analysis is performed in which identification of the bacteria is made based on a spectrum of the sample, an interference pattern used to determine cell wall thickness, and a scattering pattern used to determine cell wall roughness. An apparatus for performing the method is also disclosed, one embodiment of which incorporates a multiple sample analyzer.

Spectroscopic means and methods for identifying microorganisms in culture

A hollow waveguide for guiding laser energy, includes a proximal end for receiving the laser energy and a distal end terminating in a distal tip for delivering the laser energy to a working area. The distal end of the hollow waveguide includes an annular, converging, inner surface converging the laser energy towards the distal tip such as to concentrate the laser energy delivered through the distal tip to the working area. Also described are methods of making the hollow waveguide.

Hollow waveguide tips for controlling beam divergence and method of

A laser beam waveguide particularly useful for transmitting infrared laser radiation includes a flexible, hollow plastic tube; a metal layer on the inner surface of the hollow plastic tube; a thin dielectric film on the inner surface of the metal layer; and a flexible layer over the outer surface of the hollow plastic tube capable of absorbing infrared radiation and preventing kinking of the hollow plastic tube.

Laser beam waveguide and laser beam delivery system including same

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Ramat Hasharon, Israel

Israel Gannot