Universitè Laval

Cascades Canada Ulc

Federation Des Producteurs Acericoles Du Quebec

Ismail Fliss

Christophe Lacroix

Nathalie Comeau

Pierre Hudon

Geneviève Béland

Marie-Hélène Charest

Julie Barbeau

Imane Tahiri

Régis-Olivier Benech

Ehab Kheadr

Yann Doleyres

Dirk Bergmaier

François Bédard

Éric Biron

Michel Desbiens

Riadh Hammami

Christophe Lacroix Tahiri

Genevieve Beland

A process for the linear synthesis of a gram-positive class II bacteriocin or a variant thereof is disclosed herein. The process comprises the stepwise addition of selected amino acids to a solid support; pseudoproline positioning and reopening; and cleavage of the gram-positive class II bacteriocin or the variant thereof from the solid support to provide a linear gram-positive class II bacteriocin or variant thereof; and in situ disulfide bond formation. Various applications and uses of the synthetic bacteriocins are also disclosed. The synthetic process can also be used to synthesize variants of bacteriocins by the selective substitution of one or more amino acids and/or additions and/or deletions of selected amino acids.

Process for the linear synthesis of gram-positive class II bacteriocins and compositions and uses thereof

The present invention relates to an antimicrobial composition having activity against Gram-positive and Gram-negative bacteria. The composition is a) a composition comprising at least two organic acids selected from the group consisting of lactic acid, acetic acid, benzoic acid and citric acid; b) a composition comprising at least two bacteriocin selected from the group consisting of pediocin, Nisin and reuterin; c) a composition comprising pediocin and at least two organic acids selected from the group consisting of lactic acid, acetic acid, benzoic acid and citric acid; or d) a composition comprising reuterin and at least one organic acid selected from the group consisting of lactic acid, acetic acid, benzoic acid and citric acid. The present invention also relates to the use of said compositions for sanitizing and/or disinfecting surfaces and method thereof.

Antimicrobial compositions and uses thereof

The present invention relates to novel maple product compositions. In particular, the present invention relates to new compositions comprising maple sap, maple concentrate, maple syrup or diluted maple syrup, and probiotics, prebiotics or combinations thereof. The present invention also discloses methods for the production of maple based products, including functional drinks, comprising a composition comprising maple sap, maple concentrate, maple syrup or dilutated maple syrup, and probiotics, prebiotics or combinations thereof, as a vehicle for the delivery of probiotics and prebiotics to the gastrointestinal tract.

Symbiotic maple product compositions and methods

The present invention concerns an isolated bacteriocin, Divergicin M35, derived formM35. It also concerns a composition comprising an effective amount of Divergicin M35 and the use of that bacteriocin to kill or limit the proliferation of a microorganism.

Bacteria strain and bacteriocin produced therefrom

A method and a system is disclosed for the modulation of various characteristics of probiotic cells and for the production of probiotics having altered characteristics. Such altered characteristics include increased resistance to various stresses, drugs and chemical agents, as well as aggregation. Such a method and a system are useful for the production of probiotics with altered characteristics, which may for example provide health benefits when present in the gastrointestinal tract of an animal.

Method and system for modulation of microbial cell characteristics

Growing community of inventors

Sainte-Foy, Canada

Ismail Fliss