Mect Corporation

Isao Suda

Takayuki Ishii

Tomoya Ogawa

Mamoru Sugimoto

Masaaki Numata

Makoto Tanaka

Kenkichi Tomita

Mariko Ishii

Nobuyuki Kibushi

Ryoichi Osawa

Makiko Kasano

Tae Yasunaga

Naokazu Sugiyama

Masayoshi Ito

Yoshiyasu Shitori

Kinji Takada

Atsushi Kawamura

An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts, thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.

Method for modulating the immune system

An anti-inflammatory drug comprising as the effective component at least one compound selected from the group consisting of colominic acid, partial hydrolysis products of colominic acid and pharmaceutically acceptable salts thereof. The drug is used as a drug for renal diseases, a drug for hepatitis, an immunomodulator and a drug for inhibiting the chemotaxis of neutrophil.

Methods for inhibiting the chemotaxis of neutrophils

Anti-inflammatory agent

A hybridoma producing a monoclonal antibody specific for free N-acetylneuraminic acid or beta glycoconjugates thereof, is herein disclosed. The hybridoma can be generated by fusing (i) B cells of lymphocytes obtained by immunizing an animal with an N-acetylneuraminic acid or a beta-glycoconjugate thereof, and (ii) myeloma cells.

Monoclonal antibodies specific for free N-acetylfuraminic acid and

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Tokorozawa, Japan

Isao Suda