Eisai Company, Limited

Isao Miyoshi

Takashi Sawada

Hirokuni Taguchi

Junichi Tohmatsu

Tomiaki Morimoto

Toyohiro Kitamura

An adult T call leukemia associated cell strain can be obtained from a mixed culture of leukocytes of a rabbit and adult T cell leukemia associated antigen producing cells.

Adult T cell leukemia associated cell strain

An improved assay for an ATL virus antibody in a specimen, in which an ATL virus antigen is added to the test specimen and used as a comparative specimen. This improved method selectively assays ATL virus antibodies, and, thus, is useful in preventing and treating adult T cell leukemia.

Process for assaying ATL virus antibody and reagent therefor

A process for producing an adult T cell leukemia associated antigen is disclosed wherein an adult T cell leukemia associated antigen producing cell is treated with a surfactant. A method for assaying adult T cell leukemia associated antibodies by enzymoimmunoassay, radioimmunoassay or passive hemagglutination is also disclosed. In this method, the adult T cell leukemia associated antigen obtained by treating the adult T cell leukemia associated antigen producing cells with a surfactant is used as the antigen in the assay procedure.

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Kouchi, Japan

Isao Miyoshi