Abbott Laboratories Corporation

Isao Matsubara

Kunikatsu Shirahata

Takashi Nara

Shinji Tomioka

Hideo Matsushima

Ryo Okachi

Takao Iida

Shinzo Ishii

Masahiro Sugimoto

Derivatives of the antibiotic XK-62-2 are prepared by chemically modifying the antibiotic XK-62-2. An example of one such derivative is 1-N-[L-(-)-.alpha.-hydroxy-.gamma.-aminobutyryl]XK-62-2.

Antibiotic derivatives of XK-62-2

New antibiotic compounds, Fortimicin factors D and KE are produced by fermentation of microorganisms belonging to the genus Micromonospora. The antibiotic compounds are accumulated in the culture liquor and are isolated therefrom. A semisynthetic method of producing Fortimicin KE utilizing Fortimicin D is also disclosed.

Fortimicin factors D and KE compounds

Derivatives of the antibiotic XK-62-2 are prepared by chemically modifying the antibiotic XK-62-2. An example of one such derivative is 1-N-[L-(-)-.alpha.-hydroxy-.gamma.-aminobutyryl] XK-62-2.

Antibiotic derivatives of XK-62-2 compounds

Growing community of inventors

Machida, Japan

Isao Matsubara