Nissan Chemical Industries Limited

Sagami Chemical Research Center

Isao Hashiba

Hideo Suzuki

Kenichi Tokunaga

Fumio Suzuki

Ryozo Sakoda

Norio Tanaka

Masataka Hatanaka

Susumu Yamamoto

Hiroshi Murakami

Yoshihiro Iwasawa

Yoshihisa Watanabe

Kazuhiko Akimoto

Makoto Ishikawa

Yasuo Fukue

Kenji Suzuki

Katsuyuki Ogura

Genichi Tsuchihashi

Kiyotomo Seto

Hideo Kawashita

Masami Kozawa

Takayuki Tamura

Masaki Nagai

Shuji Tsuchiya

Hiroyuki Kousaka

Yasuo Takakuwa

Kenichi Mizusawa

Suketoshi Tsukamoto

Satoshi Yamazaki

Shuichi Fukushima

Kazuo Nagano

Tadashi Nishikimi

Shoji Fujinawa

Yoshikazu Yoshioka

Syuzi Tsuchiya

Motohito Shiratori

Kazuo Osaki

Yasuo Katsumura

Masafumi Nomura

The present invention provides a process for preparing N-methylated melamines in simple steps by using inexpensive raw materials in such a manner that the proportion of mono-type, bis-type and tris-type of the N-methylated melamines as prepared can be controlled. The process comprises reacting by heating melamine with methylamine in the presence of an acidic catalyst under pressure to substitute at least one amino group of the melamine by methylamino group.

Process for preparing N-methylated melamines

The present invention relates to a process for preparing bromoisophthalic acid compounds, particularly 5-bromoisophthalic acid compounds and 4,5-dibromoisophthalic acid compounds comprising brominating an isophthalic acid compound of the general formula (1)wherein Rand Rindependently of one another are hydrogen atom or Calkyl, with bromine in a solvent containing sulfur trioxide. The object of the invention is to provide a process for preparing bromoisophthalic acid compounds, particularly 5-bromoisophthalic acid compounds and 4,5-dibromoisophthalic acid compounds in a highly selective manner by using bromine that is industrially inexpensive.

Process for the preparing bromoisophithalic acid compound

Method for optical resolution of piperidine carboxylic acid derivative

The invention relates to a process for preparation of 4,6-diaminoresorcinol or salts thereof by reducing 4,6-bis(substituted)phenylazoresorcinol expressed by the formula &lsqb;1&rsqb;

Process for preparation of 4,6-diaminoresorcinol or salts thereof

Method of alkylating triazine derivatives

Processes for producing 4,6-bis (substituted)phenylazoresorcinols

A dialkyl dialkoxycarbonylphenylphosphonate which is useful as a resin modifier, a process for producing the same in high yield at a low cost, and a process for producing a dicarboxyphenylphosphonic acid in high yield at a low cost are described. The process for producing a dialkyl dialkoxycarbonylphenylphosphonate comprises heating and reacting a dialkoxycarbonylphenyl halide with a trialkyl phosphate in the presence of a catalyst comprising an element of group VIII of the periodic table (such as an alumina supported palladium catalyst) and hydrolyzing the obtained dialkyl dialkoxycarbonylphenylphosphonate in the presence of an acid or base to produce a dicarboxyphenylphosphonic acid.

Phenylphosphonic acid derivative and production process therefor

To provide 2,5-dicarboxyphenyl phosphonic acid and a process for the preparation thereof, comprising the steps of: forming a reaction liquid phase by supplying a 2,5-dialkylphenyl phosphonic acid, a solvent, a cobalt salt, a manganese salt and/or a cerium salt, and bromine or a bromine compound into a reaction zone; and supplying oxygen into the reaction liquid phase by bringing an oxygen-containing gas into contact with the reaction liquid phase by supplying an oxygen-containing gas into the above-mentioned reaction zone.

Derivative of phosphonic acid and process for the preparation thereof

Method of alkylating of triazine derivatives

Process for producing a 6-subsitituted 2(1H)-quinoxalinone

Disclosed herein is a process for producing N-alkylpyrazoles represented by the formula (1), which comprises reacting an alkali metal or an alkali metal-containing base with N- unsubstituted pyrazoles represented by the formula (2), to form an alkali metal salt thereof and, subsequently, reacting the obtained alkali metal salt with an alkylating agent. ##STR1##

Process for producing n-alkylpyrazoles

Disclosed herein is a process for producing N-alkylpyrazoles represented by the formula (1), which comprises reacting an alkali metal or an alkali metal-containing base with N- unsubstituted pyrazoles represented by the formula (2), to form an alkali metal salt thereof and, subsequently, reacting the obtained alkali metal salt with an alkylating agent. ##STR1## R.sup.1 : H, C.sub.1 -C.sub.4 alkyl; R.sup.2 : C.sub.1 -C.sub.4 alkyl;

Process for producing N-alkylpyrazoles

This invention relates to methods of preparing and purifying .alpha.-substituted acetic acids, which comprise treating an .alpha.aromatic-substituted acetic acid represented by a specific general formula with a weak alkali while shielding light, or subjecting an .alpha.-aromatic-substituted acetonitrile represented by a specific general formula to acid hydrolysis, followed by treatment with a weak alkali while shielding light; and treating the alkali salt of .alpha.-substituted acetic acid thus formed with a decolorizing agent.

Method of purifying .alpha.-substituted acetic acids

A process for preparing an optically active 2-(4-hydroxyphenoxy)propionic acid compound, which comprises reacting an optically active compound having the formula: ##STR1## wherein X is a chlorine atom or a bromine atom, and M is a hydrogen atom or an alkali metal atom, with hydroquinone or an alkali metal salt of hydroquinone, in the presence of an alkali metal hydroxide and water, and precipitating optically active disodium 2-(4-hydroxyphenoxy)propionate.

Process for preparing optically active 2-(4-hydroxy-phenoxy) propionic

A process for producing a 2-(4-hydroxyphenoxy) propionate derivative represented by the formula: ##STR1## where Alk is a C.sub.1 -C.sub.5 alkyl group, which comprises reacting a phenoxy propionate derivative represented by the formula: ##STR2## where Alk is as defined above, with a peroxide to obtain a formate derivative represented by the formula: ##STR3## where Alk is as defined above, and hydrolyzing the formate of the formula III.

Process for producing 2-(4-hydroxyphenoxy) propionate derivatives

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Funabashi, Japan

Isao Hashiba