Kumiai Chemical Industry Co., Ltd.

Toyo Jozo Kabushiki Kaisha

Kumiai Kagaku Kogyo Kabushiki Kaisha

Isao Chiyomaru

Kiyoshi Takita

Seigo Kawada

Koichi Sato

Ichiro Kimura

Kazuo Jikihara

Shuichi Takayama

Shigekazu Itoh

Noriyasu Takayanagi

Kazuo Nishio

Kazuko Yamamoto

Katsuo Anma

Hiroshi Ohno

Tadayoshi Hirano

Osamu Tada

Hironari Sugiyama

Tetsuo Horii

Yoshitaka Suda

Kunihiko Fujimori

Shigeru Tsuchiya

Koyata Niita

Hidetoshi Sugiyama

Itsuki Okuda

Hisaaki Yamamoto

Hideo Ito

Compounds of the formula wherein R is ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 are the same or different and are selected from the group consisting of hydrogen, chlorine, bromine, lower alkyl, lower alkoxy and naphthyl, provided that when R.sub.1 is lower alkyl, R.sub.2 and R.sub.3 are hydrogen, chlorine, bromine or lower alkoxy, or a pharmaceutically acceptable salt thereof, have anti-carrageenin edema activity, and are useful as anti-inflammatory agents and immuno modulators. They are produced by reacting an amide of the formula ##STR2## wherein R has the same meanings hereinabove, with N,N'-ethylene thiourea.

2,3-di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts,

Compounds of the formula ##STR1## wherein R is ##STR2## in which R.sub.1, R.sub.2 and R.sub.3 are the same or different and are selected from the group consisting of hydrogen, chlorine, bromine, lower alkyl, lower alkoxy and naphthyl, provided that when R.sub.1 is lower alkyl, R.sub.2 and R.sub.3 are hydrogen, chlorine, bromine or lower alkoxy, or a pharmaceutically acceptable salt thereof, have anti-carrageenin edema activity, and are useful as anti-inflammatory agents and immuno modulators. They are produced by reacting an amide of the formula ##STR3## wherein R has the same meanings hereinabove, with N,N'-ethylene thiourea.

2,-3-Di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts,

A herbicidal composition which comprises a phenoxyphenoxy unsaturated derivative having the formula: ##STR1## wherein X represents a halogen atom or CF.sub.3 ; Y represents a hydrogen atom or a halogen atom; and Z represents --COOR, --COR', --COOH, --CH.sub.2 OH, or --CH.sub.2 OR''.

Phenoxyphenoxy unsaturated derivatives and herbicidal composition

Organic phosphoric acid ester derivatives represented by the formula (I): ##STR1## wherein R and R', which may be the same or different, each represents an alkyl group, and A represents a group of atoms necessary to complete together with the two carbon atoms to which they are attached, a 6-membered heterocyclic group containing an oxygen atom as a heteroatom; a process for preparing the same and insecticidal, miticidal or nematocidal compositions containing the same as an active ingredient are disclosed; the compositions exhibit a high ability to control insect pests, mites, nematodes and unhygienic insects harmful to agricultural and horticultural crops.

Organic phosphoric acid ester derivatives, a process for preparing the

A herbicidal composition which comprises a herbicidally effective amount of a phenoxyphenoxy derivative having the formula ##STR1## wherein X represents a halogen atom or CF.sub.3 ; Y represents a hydrogen atom or a halogen atom; and Z represents --COSR.sup.1 and R.sup.1 represents lower alkyl, phenyl, chlorophenyl, chlorobenzyl or methoxybenzyl; in combination with a suitable carrier is disclosed.

Trifluoromethylphenoxy phenoxy crotonic acid derivatives of the formula ##STR1## wherein X represents hydrogen or halogen atom, and R represents an alkyl, haloalkyl, alkenyl haloalkenyl or alkynyl group are disclosed. These compounds disclose herbicidal activity.

Phenoxyphenoxy crotonic acid derivatives and herbicidal composition

2-Alkylbenzanilide is produced by reacting an alkyl 2-alkylbenzoate having the formula ##STR1## wherein X represents a lower alkyl group and R represents a lower alkyl group with an aniline having the formula ##STR2## wherein Y represents hydrogen atom, an alkoxy, alkenyloxy, alkynyloxy, benzyloxy or halobenzyloxy group in the presence of an alcoholate in a solvent which is hardly azeotropically distilled with the by-product of alcohol.

Process for producing 2-alkylbenzanilide

Method of controlling fungal diseases in plants and Compositions effective therefor are shown. The method comprises the steps of applying an effective amount of a substituted derivative of 1,1,-dichloroalkene-1 of the general formula

Method of controlling fungal diseases in plants and compositions

An agricultural germicide having the formula ##SPC1## Wherein R represents C.sub.1.sub.-12 alkyl, alkenyl, alkynyl, benzyl or chlorobenzyl.

Agricultural substituted 2-methylbenzanilide germicide

2,4-Dimethyl-3-carboxanilido- or naphthyl amido-furan of the formula ##SPC1## Involving the reaction of ##SPC2## Or ##SPC3## Wherein X represents a halogen atom, an alkyl group, hydroxyl group, an alkoxyl group, an alkenyloxy group, trifluoromethyl group, phenyl group, cyano group, acetyl group, a metal substituted hydroxy group or a combination thereof are useful as agricultural germicides, fungicides, insecticides and nematodicides.

2,4-Dimethyl-3-carboxyanilidofuran compounds

Novel thioureidobenzene compounds having the general formula ##EQU1## wherein R and R' are lower alkyl groups and X is oxygen or sulfur atom is prepared by reacting a compound having the general formula ##EQU2## wherein Y is chlorine or bromine, with a compound having the general formula ##EQU3## wherein M is ammonium or an alkali metal. These compounds have high miticidal and fungicidal activity.

Method for controlling mites and thioureidobenzene phosphates

An agricultural germicide having the formula ##SPC1## Wherein R represents C.sub.1-12 alkyl, alkenyl, alkynyl, benzyl or chlorobenzyl.

Growing community of inventors

Shimizu, Japan

Isao Chiyomaru