Centre National De La Recherche Scientifique

Pierre Fabre Medicament

Institut De Recherche Pour Le Developpement (ird)

Institut De Recherche Pour Le Development (ird)

Institut De Recherche Pour Le Developpement

Isabelle Carletti

Georges Massiot

Cécile Debitus

The present invention relates to a compound of the following formula (I) or to a salt, hydrate, or pharmaceutically acceptable solvate thereof, in which R is a monosaccharide or disaccharide residue. The hydroxyl functions of the monosaccharide or disaccharide residue are, independently, optionally substituted for a (C-C) alkyl or &#x2014;C(O)NH&#x2014;(C-C) alkyl group. The invention also relates to the method for preparing said compound, to a pharmaceutical composition containing same, and to the use thereof as a drug, particularly for cancer treatment. 

Macrolides useful as anticancer agents

The present invention relates to a polyketide molecule of the following formula (I): or a pharmaceutically acceptable salt thereof,

Polyketide molecules as anticancer agents

Growing community of inventors

Toulouse, France

Isabelle Carletti