Sanofi

Hexcel Composites Limited

Sanofi-aventis

Isabelle Blanc

Olivier Duclos

Gary Mccort

John Ellis

Paul Mackenzie

David Allan Tilbrook

Emilie Fisset

Antoine Alam

Sandrine Biscarrat

Françoise Bono

Emille Fisset

Lucien Fiore

Bernadette Tizon

Paul MacKenzie

Gary Mc Cort

This invention is related to the use of inhibitors of vascular endothelial growth factor receptor 3 for treating hepatocellular carcinoma.

Use of VEGFR-3 inhibitors for treating hepatocellular carcinoma

A process for the manufacture of a prepreg comprising feeding a layer of unidirectional conductive fibers having a defined width, bringing into contact with a first face of the fibers a first layer of resin comprising thermosetting resin, and compressing the resin and fibers together by passing over one or more impregnation rollers, wherein the pressure exerted onto the conductive fibers and resin does not exceed 40 kg per centimeter of the width of the conductive fibers, and the resin being in sufficient amount for the resin to enter the interstices of the fibers and leave a first outer layer of resin essentially free of unidirectional conductive fibers.

Process for manufacturing composite materials

The disclosure relates to 7-alkynyl-1,8-naphthyridones of formula (I): wherein R, R, R, and Rare as defined in the disclosure, to compositions containing them, to processes for preparing them, and to their use in therapeutics.

Derivatives of 7-alkynyl-1,8-naphthyridones, preparation method thereof and use of same in therapeutics

Growing community of inventors

Paris, France

Isabelle Blanc