Other

Duke University

University of Central Florida Research Foundation, Inc.

Isabel Lauren Jackson

Zeljko Vujaskovic

Sudipta Seal

Michael D Kaytor

John L Zenk

Soumen Das

Geoffrey E Schroeder

A method for mitigating erectile dysfunction as an adverse side effect of radiation therapy for prostate cancer, comprising administration of a therapeutic dosage of genistein to a patient diagnosed with prostate cancer throughout only a primary administration period that commences a defined period of up to two weeks prior to commencement of radiation therapy for prostate cancer and extends beyond conclusion of the radiation therapy.

Administration of a therapeutic amount of genistein to mitigate erectile dysfunction resulting from radiation therapy for prostate cancer only throughout a defined administration period commencing shortly before and concluding after radiation therapy

Methods of mitigating the effects of radiation exposure or providing a radioprotective effect in a subject are provided herein. The methods include administering a therapeutically effective amount of cerium oxide nanoparticles to the subject to mitigate the effects of radiation exposure or to offer a radioprotective effect to the subject. The cerium oxide nanoparticles are suitably less than 20 nm in diameter and have over 50% of the cerium in the 3+ oxidation state.

Methods of using cerium oxide nanoparticles to mitigate or protect against radiation injury

Growing community of inventors

Baltimore, MD, United States of America

Isabel Lauren Jackson