Varian Medical Systems, Inc.

Varian Medical Systems Particle Therapy Gmbh & Co Kg

Varian Medical Systems International Ag

Varian Medical Systems Particle Therapy Gmbh

Siemens Healthineers International Ag

Varian Medical Systesm Particle Therapy Gmbh & Co. Kg

Varian Medical System Particle Therapy Gmbh

Varian Medical Systems Therapy Gmbh & Co Kg

Isabel Huth

Markus Bach

Christel Smith

Timo K Koponen

Perttu Niemela

Reynald Vanderstraeten

Holger Goebel

Juergen Heese

Lei Dong

Franko Piskulich

Tina Pfeiler

Eric Abel

Michael Matthew Folkerts

Pierre Lansonneur

Viljo Petaja

Michiko Rossi

Jan H Timmer

Reynald Vanderstraten

Roni Hytonen

Reynald Van Der Straeten

Arturs Meijers

Perttu Niemelae

Holger GÖBEL

A computer implemented method of determining a resultant treatment plan for a proton radiation therapy system based on given dose volume constraints, wherein the resultant treatment plan is optimized for treatment time comprises accessing the dose volume constraints and range information, wherein the range information indicates acceptable deviations from the dose volume constraints. Based on the proton radiation therapy system, the method further comprises accessing machine configuration information comprising a plurality of machine parameters that define a maximum resolution achievable in irradiating a patient. Further, the method comprises iteratively adjusting the plurality of machine parameters to values which decrease the maximum resolution and simulating a plurality of candidate treatment plans to generate a plurality of treatment plan results, wherein each treatment plan result comprises: a respective treatment time and a respective plan quality. Finally, the method comprises selecting a resultant treatment plan with the shortest treatment time.

Method and apparatus for performing irradiation time optimization for intensity modulated proton therapy during treatment planning while maintaining acceptable irradiation plan quality

Dose analysis radiotherapy systems and methods for determine delivered radiotherapy dose, dose rate, irradiation time and position information and planned radiotherapy dose, dose rate, irradiation time and position information. The dose analysis systems and methods further compare the as delivered dose, dose rate, irradiation time and position information to the planned dose, dose rate, irradiation time and position information to generate a graphical representation of one or more of the delivered dose, dose rate, irradiation time and position information versus planned dose, dose rate, irradiation time and position information.

Radiotherapy dose analysis methods and systems

Presented systems and methods enable efficient and effective robust radiation treatment planning and treatment, including analysis of dose rate robustness. In one embodiment, a method comprising accessing treatment plan information, accessing information corresponding to an uncertainty associated with implementation of the radiation treatment plan, and generating a histogram, wherein the histogram conveys a characteristic of the treatment plan including an impact of the uncertainty on the characteristic. The histogram can be a dose rate volume histogram and can be utilized to test a degree of robustness of a treatment plan (e.g., including allowance for uncertainty scenarios, etc.). The uncertainty can be associated with potential variation associated with tolerances (e.g., radiation system/machine performance tolerance, patient characteristic tolerances, etc.) and set up issues (e.g., variation in initial system/machine set up, variation patient setup/position, etc.).

Analysis of dose rate robustness against uncertainties in radiation treatment planning

Treatment fields can be produced as part of a treatment plan that achieves a desired balance between field delivery time and dose based on machine parameters and knowledge, such as machine-specific beam production, transport and scanning logic, and/or a maximum treatment time value. The treatment parameters can be adjusted using a graphical user interface so that treatment time or dosimetry is prioritized. As a result, the overall treatment time is reduced, and hence treatment quality and patient experience are improved.

System and method for radiotherapy field delivery time optimization

In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area.

Time optimized radiation treatment

To overcome the difficulties inherent in conventional proton therapy systems, new techniques are described herein for synchronizing the application of proton radiation with the periodic movement of a target area. In an embodiment, a method is provided that combines multiple rescans of a spot scanning proton beam while monitoring the periodic motion of the target area, and aligning the applications of the proton beam with parameters of the periodic motion. For example, the direction(s) and frequency of the periodic motion may be monitored, and the timing, dose rate, and/or scanning direction and spot sequence of the beam can be adjusted to align with phases in the periodic motion.

System and method for in-layer synchronization for fast spot rescanning

To overcome the difficulties inherent in conventional proton therapy systems, new techniques are described herein for synchronizing the application of proton radiation with the periodic movement of a target area. In an embodiment, a method is provided that combines multiple rescans of a spot scanning proton beam while monitoring the periodic motion of the target area, and aligning the applications of the proton beam with parameters of the periodic motion. For example, the direction(s) and frequency of the periodic motion may be monitored, and the timing, dose rate, and/or scanning direction and spot sequence of the beam can be adjusted to align with phases in the periodic motion

Growing community of inventors

Kuerten, Germany

Isabel Huth