Lt Industries

Other

Isaac J Landa

Michael M Anthony

George E Toth

Ronald Shideler

An fixed grating, detector-array type analyzer rapidly multiplexes multiple channels. The analyzer comprises a light source, a detector array-type spectrograph, and an optical multiplexer. The multiplexer can select from one of a plurality of channels. Further, the multiplexer can convolute light passing through it with a reference spectrum for calibration and wavelength drift compensation. Rapid multiplexing is achieved using a fiber optic slit array which 'perpendicularly multiplexes' the plurality of channels.

Rapid scanning spectrographic analyzer

A modular probe is provided to enable introduction of light to a sample to be analyzed by an electro-optical device. The probe of the present invention may include an optical rod or other device for propagating light, an optical barrel which in part surrounds the optical rod, and a sleeve which is provided to attach the probe to a source of light such as a fiber optical bundle. The probe may be fitted with a bidirectional focusing adapter and a reflective tip. A transverse probe is also described.

Probe for transmitting and receiving light from a sample

The invention is a multiplexer which enables light to be sent to and received from samples for simultaneous analysis. A multiplexer is described which uses a transverse probe to reflect light at an angle into an optical rod. The transverse probe is selectively rotated to transmit light to a second optical rod. Various numbers of optical rods may be used in the linear mutliplexer. A multiplexer is also described in which a conjugate optical barrel is utilized to selectively reflect light to various probes.

Multiplexer for use with a device for optically analyzing a sample

An apparatus uses a rapid and efficient method for conducting fluorescence measurements, such as immuno assay, of a plurality of samples of a substance using pulsed or continuous light energy, front-end fluorescent optics, a mechanism which allows for lateral and tranverse scanning of rows and columns of wells, and spectra emission analysis of the spectra from the excited samples.

Rapid and automatic fluorescence immunoassay analyzer for multiple

An electro-optical system for rapid, accurate spectral analysis of the reflectivity or transmissivity of samples. A concave, holographic diffraction grating is oscillated at high speed to provide a rapid scanning of monochromatic light through a spectrum of wavelengths. The grating drive system is an electrically driven mechanical oscillator which utilizes the back EMF of the oscillator motor to maintain oscillation at the desired amplitude and frequency. A passive optical shutter mounted to the grating alternately blocks the light entering and exiting the monochrometer as the grating is oscillated. The resultant dark period is utilized by the system to provide a reference offset value and to control cooling of the detectors. A unique phase-locked loop circuit is employed to provide sample commands at precisely determined intervals to correctly correlate the spectral data with the output of the monochrometer. Source and exit optics are employed to optimally shape the light passing through the system. A unique detection head is provided to allow measurement of light transmission or reflectance with only slight modification of the system. An optical fiber is used to divert light from the beam at or near the sample. This light is electronically detected and the electronic detection signal is used to adjust the gain of the sample signal so as to compensate for atmospheric bands, temporal variations, and system response. This provides a true double (dual) beam operation.

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Potomac, MD, United States of America

Isaac J Landa