Pioneer Hi-bred International, Inc.

E.i. Dupont De Nemours and Company

University of California

Irina Elleskaya

Carl R Simmons

Billy Fred McCutchen

James Kevin Presnail

Rafael Herrmann

Eric J Schepers

Nasser Yalpani

Janet Ann Rice

Daniel J Altier

Tamas Torok

Jennie Hunter-Cevera

Natalia Ellanskaya, Legal Representative

Glen Dahlbacka

Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include novel amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from microbial fermentation broths. Nucleic acid molecules comprising nucleotide sequences that encode the antipathogenic polypeptides of the invention are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Transformed plants, plant cells, seeds, and microorganisms comprising a nucleotide sequence that encodes an antipathogenic polypeptide of the invention, or variant or fragment thereof, are also disclosed.

Antifungal polypeptides

Growing community of inventors

Kyiv, Ukraine

Irina Elleskaya