Other

Linguaflex, Inc.

Mount Sinai School of Medicine

Cornell University

Med-el Elektromedizinische Geraete Gmbh

Chain Orthopedics, LLC

Sanders, Ira

Ira Sanders

Cliff Dwyer

Rosemary Aquila-Sanders

Jon Buzzard

Asif Amirali

Werner Lindenthaler

Norm G Ducharme

Christopher M Shaari

Timothy J Langloss

Paul Viola

Rosemary Aquila

A tissue retractor including a head member, an anchor member, and a shaft extending between the head member and the anchor member. The shaft has an elastic portion and an adjustment portion. The elastic portion is made of a first material and the adjustment portion is made of a second different material. The adjustment portion has a first locking element and the anchor member has a second locking element. The first locking element and the second locking element are configured to adjust the length of the shaft that extends between the head member and the anchor member. Also, a tissue retractor including a head member having a window and an anchoring segment surrounding the perimeter of the window, an anchor member, and a shaft extending between the head member and the anchor member, the shaft having an elastic portion and an adjustment portion.

Tongue retractor

Improved chain saws, components for chain saws, methods of making chain saws and components, and methods of using chain saws and components are disclosed. In some embodiments, a chain saw comprises a saw bar and a plurality of links, wherein a first link has a hook that engages a recess of a second link, thereby coupling the first link and the second link and allowing them to articulate without decoupling. The saw bar may have a rail, and the links may have grooves such that the links straddle and ride over the rail. The rail may have a projection and the grooves of the links may have notches accommodating the projection such that the projection prevents dislocation of the links. The links may have conical or pyramidal cutting teeth. The chain may be bidirectional. Robotic and automated operation of saws and other instruments are also disclosed.

Chain saws, components for chain saws, and systems for operating saws

An implantable tissue retractor for treatment of a breathing disorder and related methods. The implantable tissue retractor comprises a shaft sized for insertion into a soft tissue located in a patient's oral cavity or pharynx. The implantable tissue retractor also comprises a retractor member at or near a first end of the shaft. The implantable tissue retractor also comprises a removable coupler connected at or near a second end of the shaft. At least one of a portion of the shaft or the retractor member is positionable on a surface of the soft tissue. At least one of the shaft, retractor member, or removable coupler is adjustable to vary a force to prevent a deformation of at least a portion of the soft tissue to prevent obstruction of the patient's airway.

Methods and devices for treating sleep apnea

The device relates to methods and devices for the treatment of obstmctive sleep apnea syndrome.

Method and device for the treatment of obstructive sleep apnea and snoring

Disclosed herein are methods and compositions for treatment of skin disorders and diseases using botulinum toxin targeted to nerve ganglia. It has been unexpectedly found that botulinum neurotoxin (BoNT) can decrease the severity of numerous skin disorders by application to nerve ganglia including but not limited to the parasympathetic, sympathetic, and sensory ganglia

Skin therapeutics

Embodiments of the invention include methods and devices to prevent or treat upper airway disorders in mammals related to impaired airflow. One aspect of this invention is a tongue retractor (LTR) that indirectly retracts tongue base by its implant site in the frenulum area. This simplifies the insertion, adjustment and maintenance of the device. Another aspect of this invention describes a highly localized and fully implantable LTR that is inserted into the base of tongue to stiffen lax surface mucosa or mechanically couple it to internal tongue structures. Another aspect of this invention is an LTR inserted in or around the pharyngoglossal fold. This site allows retraction and stiffening of tongue base tissue as well as the soft palate and lateral pharyngeal wall.

Methods and devices for treating sleep apnea and snoring

A method is disclosed for blocking or reducing a physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a neurotoxin (CnT) derived fromsp.

Treatment of mammalian physiological reaction of IgE antibodies present in said mammal upon contact with the corresponding antigen

Methods and devices to prevent and/or treat breathing disorders (e.g., upper airway disorders) in mammals related to impaired airflow are described. Methods and devices apply force to soft tissue that avoids obstruction of airflow in the mammel's airway. Breathing disorders that are avoided by the methods and/or devices include apnea.

A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of a therapeutically effective amount of a neurotoxin (CnT) derived fromsp.

Compositions and methods of modulating cellular function and treatment of disease in mammals comprising locally administering a regulated SNARE inhibitor and a translocating agent to the mammal. Regulated SNARE inhibitors include clostridial neurotoxins, tetanus neurotoxin and their free light chain portions and IgA protease. Translocating agents include acids, encapsulating vectors, and transduction domains.

Cell membrane translocation of regulated snare inhibitors, compositions therefor, and methods for treatment of disease

Airway disorders in a horse are relieved by electrical stimulation of the airway tissue. Particular disorders and techniques include electrical stimulation to relieve laryngeal hemiplegia. A pacemaker processor generates an electrical treatment signal to be applied to upper airway tissue of the horse for treating the upper airway disorder. One or more stimulation electrodes interfaces with the upper airway tissue for delivering the treatment signal to the upper airway tissue.

Equine airway disorders

A method is disclosed for blocking or reducing physiological reaction in a mammal to the interaction of IgE antibodies present in said mammal upon contact with the corresponding antigen, by the administration to said mammal of therapeutically effective amount of a neurotoxin (CnT) derived from Clostridia sp.

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North Bergen, NJ, United States of America

Ira Sanders