The City University of New York

Lockheed Martin Corporation

City College of New York

Research Foundation of Cuny

Medical Optical Imaging, Inc.

Iosif Semen Zeylikovich

Robert R Alfano

Yury Budansky

Wubao Wang

Vincent P Benischek

Jamal H Ali

Michael Victor Klibanov

Andrey Anatolyevich Kharisov

A system and method for producing a multiple optical channel source (MOCS). The method includes producing the SC in a medium using at least one femto-second or pico-second optical input pump pulse; splitting input pump pulse or resultant output SC pulse(s) into a plurality of collinear pulses; applying a time delay &#x3c4; between the least one of input pump pulse or SC pulses; and producing a MOCS by the spectral interference of the plurality of SC pulses. The system includes a laser producing femto-second or pico-second pump pulses, a medium with a high value of the &#x3c7;nonlinear response to produce spectrally coherent SC, an optical system for delivery of laser pump pulses into the SC producing medium, an optical system for splitting the input pump pulses or output SC pulses into a plurality of collinear pulses, and a means for applying a time delay &#x3c4; between the plurality of pump or SC pulses.

Method and apparatus for producing a multiple optical channel source from a supercontinuum generator for WDM communication

The present invention provides systems and methods for non-destructively detecting material abnormalities beneath a coated surface, comprising a mid-infrared (MIR) illumination unit for illuminating an area of the coated surface, and an MIR 2-D imager, which includes an MIR CCD or CMOS camera, for capturing an image of a material abnormalities under the illuminated area of the coated surface. In addition, the system may further comprise a scanning unit for moving the system to a next area.

Systems and methods for non-destructively detecting material abnormalities beneath a coated surface

Methods and apparatus are provided for detecting an abnormality in a host medium, such as a tumor within a patient's breast. The host medium is initially illuminated at a plurality of different positions with light of at least two different wavelengths. Following the propagation of the signals through the host medium, the amplitude and phase of the signals are detected and, based upon the detected signals, a shadow image can be created in which the abnormality is depicted as a suspicious region. Once a suspicious region has been identified, at least that portion of the host medium that contains the suspicious region is again illuminated with frequency-swept modulated signals of at least two different wavelengths generated by the light source and modulated by a modulator, such as a network analyzer. Based upon the detected signals that have propagated through at least that portion of the host medium that includes the suspicious region, a P-criteria can be determined that is dependent upon the coefficient of absorptivity of the host medium and embedded abnormalities. Likewise, an S-criteria can be determined based upon concentrations of oxygenated hemoglobin and deoxygenated hemoglobin. Based upon at least these criteria which reflect physiological parameters of the host medium and embedded abnormalities as well as the possible comparison of the shadow images to an x-ray image of the host medium, the abnormality can be characterized. In addition, an apparatus is provided that facilitates the compression of a patient's breast in order to improve the resulting images.

Method and apparatus for detecting an abnormality within a host medium utilizing frequency-swept modulation diffusion tomography

The present invention provides systems and methods for non-destructively detecting material abnormalities beneath a coated surface, comprising a mid-infrared (MIR) detection unit for illuminating an area of the coated surface and detecting light reflected from the illuminated area of the coated surface, and a processing unit for producing an image from optical characteristics received from the MIR detection unit. In addition, the system may further comprise a scanning unit for moving the MIR detection unit to a next area.

A system and method for performing selected optical measurements on a sample is provided utilizing an optical coherence domain reflectometer which includes a diffraction grating. A broad band light source produces light having a short coherence length. A beamsplitter splits the light into a signal beam and a reference beam. A reference mirror is disposed to receive the reference beam. A lens brings the signal beam to focus on the sample. A diffraction grating receives reflections from the sample and from the reference mirror, the reflections being incident on the diffraction grating with respect to said diffraction grating normal such that a positive diffraction order from one of the reflections and a negative diffraction order from the other one of the reflections and a negative diffraction order from the other one of the reflections propagate along a common path. A lens collects the diffracted order from the diffraction grating directed along the common path and brings the diffracted orders to focus on a detector, the detector producing an output of said positive and negative diffracted orders received. A computer processes the output from the detector. In other versions of the invention, reflections from the sample are not directed onto the diffraction grating but instead are combined with a diffracted order from reflections from the reference mirror.

System and method for performing selected optical measurements utilizing a position changeable aperture

Performing selected optical measurements with optical coherence domain reflectometry

A system and method for performing selected optical measurements on a sample is provided utilizing an optical coherence domain reflectometer which includes a diffraction grating. A broad band light source produces light having a short coherence length. A beamsplitter splits the light into a signal beam and a reference beam. A reference mirror is disposed to receive the reference beam. A lens brings the signal beam to focus on the sample. A diffraction grating receives a reflection from the sample and from the reference mirror, the reflections being incident on the diffraction grating with respect to said diffraction grating normal such that the positive and negative first or second or higher diffraction orders from said reflections received propagate along a normal to said diffraction grating. A lens collects the diffracted orders from the diffraction grating and brings the diffracted orders to focus on a detector, the detector producing an output of said positive and negative first diffracted orders received. A computer processes the output from the detector.

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Charlotte, NC, United States of America

Iosif Semen Zeylikovich