I.b.r. Israeli Biotechnology Research Ltd.

Israeli Biotechnology Research Ltd.

Inon Perry

Etienne Soudant

Lea Bezalel

Meira Ziv

Judith Paltiel

Aviv Shaish

Ami Ben-Amotz

Fabien Havas

Olga Ben-Chitrit

Hedva Schickler

Yuki Hata

Ilana Kachko-Chernetsky

Eyal Kalo

Lea Von Oppen-Bezalel

Alex Aliluiko

Ofir Ramot

Liki Von Oppen-Bezalel

Liki Von Oppen Bezalel

Fumio Maniwa

Raffi Arnon

Akemi Takayama

Fishbein Manor Danit

Iliana Kachko-Chernetsky

Danit Fishbein Manor

The present invention relates to extracts derived from plants and/or fractions thereof, compositions comprising same and use thereof in protecting tissues from damages caused by exogenous toxins. In particular, the present invention relates to polar extract and/or fraction thereof derived from, compositions comprising same and use thereof in protecting tissues comprising epithelial cell from the deleterious effect of exogenous toxins, particularly toxins originating from environmental pollution.

extracts and use thereof

The present invention provides compositions comprising extracts of Jojoba () in a polar solvent that are effective in promoting the barrier functions of the skin, useful for improving skin integrity, health and appearance and as anti-aging agent.

Jojoba extract useful in improving skin barrier functions

The present invention relates to use of carotenoid preparations for promoting skin whitening. Particularly, the present invention discloses that a combination of phytoene and phytofluene is effective in whitening skin. The present invention further relates to carotenoid compositions comprising a combination of phytofluene and phytofluene effective in whitening skin and at least one additional carotenoid, particularly carotenoids devoid of highly intense color.

Carotenoid compositions useful for whitening skin

A preparation comprising the carotenoids phytoene and phytofluene in an amount which, in combination, is effective in preventing various kinds of damage resulting from oxidation and exposure to UV light is provided. The preparation is essentially colorless and may be used as a topical cosmetic or pharmaceutical preparation as well as an additive in food preparations. In addition, a method for producing substantive amounts of phytoene and phytofluene from carotenoid producing organisms is described as well.

Carotenoid preparation

A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.

Methods of inhibiting proliferation of cells

Anti proliferative preparations

A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation. A preferred dormant preparation is prepared from a water extract of Narcissus (daffodil) bulb.

Anti-proliferative preparations

Growing community of inventors

Tel Aviv, Israel

Inon Perry