Rohm and Haas Company

Dow Global Technolgoies LLC

Intrexon Corporation

Dow Silicones Corporation

Conopco, Inc.

Bayer Cropscience Ag

Union Carbide Corporation

Fmc Corporation

Precigen, Inc.

Inna Shulman

Fanwen Zeng

Robert Eugene Hormann

Tian Lan

Xiaodong Lu

Isabelle Van Reeth

Helene Dihang

Sheela K Chellappan

Marc Eeman

Walter H Yeager

John W Lyga

George Theodoridis

Thomas G Cullen

Ariamala Gopalsamy

Robert N Henrie, Ii

Ian R Silverman

Daniel H Cohen

Rolf Hilfiker

Paul E Rensner

Stephen F Donovan

Ping Ding

David Rosen

Y Larry Zhang

Susan Margaret De Paul

Guozhi Wang

Michaeleen L Pacholski

Seong Jae Yu

Qun Zhang

Dennis L Warkentin

Eva Rödel

Ralph Craig Even

Liang Chen

Curtis Alan Schwartz

Jodi M Mecca

Dale C Schmidt

Wei Gao

Lyndsay M Leal

Ying O'Connor

Matthew Jeletic

Kinjalbahen Joshi

Neil Scott Shaw

Bryan L McCulloch

Nicholas John Ainger

Adam Peter Jarvis

Pierre Starck

Wenjun Xu

Hilda G Buss

Sally Elizabeth Wood

Benjamin Yezer

Steven Shunxiang Zhang

Sokhomari S Suon

Susan M Depaul

Eva Rodel

Asghar Akber Peera

Muhunthan Sathiosatham

Jason S Fisk

Peilin Yang

Tzu-Chi Kuo

James Pawlow

Jennifer Koenig

Joanna Susan Dawson

Stephen Shunxiang Zhang

Tanvi S Ratani

Rachael M Smith

Bryan L Mcculloch

Personal care formulation is provided having multistage polymer, comprising: acrylate rich stage comprising: (a) structural units of monomer selected from Calkyl (meth)acrylates and structural units of first carbosiloxane monomer of formula (I); and (b) carbosiloxane rich stage, comprising: structural units of second carbosiloxane monomer of formula (I); wherein a is 0 to 3; wherein d is 0 or 1; wherein Ris selected from hydrogen, Calkyl group and aryl group; wherein Ris selected from hydrogen and Calkyl group; wherein Ris —O—Si(CH)group; wherein Y is selected from formula (II), (III) and (IV); wherein Rand Rare selected from hydrogen and methyl group; wherein Rand Rare Calkylene group; wherein Ris Calkyl group; wherein b is 0 to 4 and wherein c is 0 or 1; and wherein the first and second carbosiloxane monomer of formula (I) are same or different.

Personal care formulation

A polymer blend is provided comprising: a single stage polymer and a silicone-grafted vinyl copolymer; wherein the single stage polymer comprises: structural units of a monoethylenically unsaturated non-ionic monomer; structural units of a monoethylenically unsaturated carboxylic acid monomer; and structural units of a multiethylenically unsaturated monomer having at least two ethylenically unsaturated groups per molecule; and wherein the silicone-grafted vinyl copolymer, comprises: structural units of a vinyl monomer; and structural units of a carbosiloxane dendrimer of formula (I). Also provided is a suncare formulation comprising the polymer blend in a dermatologically acceptable carrier with a suncare active.

Suncare formulation

A color cosmetic formulation is provided comprising: a color ingredient and a polymer blend, comprising: a single stage polymer and a silicone-grafted vinyl copolymer; wherein the single stage polymer comprises: structural units of a monoethylenically unsaturated non-ionic monomer; structural units of a monoethylenically unsaturated carboxylic acid monomer; and structural units of a multiethylenically unsaturated monomer having at least two ethylenically unsaturated groups per molecule; and wherein the silicone-grafted vinyl copolymer, comprises: structural units of a vinyl monomer; and structural units of a carbosiloxane dendrimer of formula (I).

Color cosmetic formulation

A personal care formulation is provided comprising: multistage polymer, comprising: acrylate rich stage comprising: (a) structural units of monoethylenically unsaturated non-ionic, acrylate rich stage monomer selected from Calkyl (meth)acrylates and mixtures thereof; and (b) carbosiloxane rich stage, comprising: structural units of carbosiloxane monomer of formula (I), wherein a is 0 to 3; wherein d is 0 or 1; wherein Ris selected from hydrogen, Calkyl group and aryl group; wherein Ris selected from hydrogen and Calkyl group; wherein Ris —O—Si(CH)—O—Si(CH)group; wherein Y is selected from formula (II), (III) and (IV); wherein Rand Rare selected from hydrogen and methyl group; wherein Rand Rare a Calkylene group; wherein Ris Calkyl group; wherein b is 0 to 4 and wherein c is 0 or 1.

A polymer blend is provided comprising: (A) multistage polymer, comprising: acrylate rich stage comprising: structural units of monoethylenically unsaturated non-ionic, acrylate rich stage monomer selected from Calkyl (meth)acrylates and mixtures thereof; and carbosiloxane rich stage, comprising: structural units of carbosiloxane monomer of formula (I); and (B) silicone-grafted vinyl copolymer, wherein the silicone-grafted vinyl copolymer, comprises: structural units of a vinyl (B) monomer; and structural units of a carbosiloxane dendrimer of formula (V). Also provided are personal care formulations comprising the polymer blend.

Polymer blend

A personal care composition is provided, comprising: a vehicle; a cosmetically acceptable oil; and a cationic polymer comprising structural units of acrylamide monomer; structural units of N,N-dimethyl acrylamide monomer; and structural units of monoethylenically unsaturated monocationic monomer; wherein the cationic polymer comprises <10 mol % structural units of multiethylenically unsaturated cationic monomer; wherein the cationic polymer comprises <30 wt % structural units of ester containing monomers; wherein the cationic polymer comprises <1 mol % structural units of ethylenically unsaturated monomers containing a moiety selected from the group consisting of epoxy, anhydride, imide, lactone, carboxylic acid, sulfonic acid and isocyanate; wherein the cationic polymer comprises <0.1 mol % structural units of a reactive siloxane; and wherein the personal care composition comprises <0.05 wt % water soluble, organic, ampholytic polymer conditioning agent. Also provided is a method of using a personal care composition.

Personal care composition

An acidic aqueous shampoo composition, which comprises: (I) a cleansing surfactant selected from the group consisting of anionic surfactant, zwitterionic or amphoteric surfactant and nonionic surfactant; (II) an emulsified silicone, (III) an anti-settling, thickening polymer, wherein the anti-settling, thickening polymer, comprises: (a) 40 to 74.5 wt % of structural units of Calkyl acrylate; (b) 20 to 50 wt % of structural units of methacrylic acid; (c) 0.3 to &#x3c;5 wt % of structural units of 2-acrylamido-2-methyl-propane sulfonic acid (AMPS); (d) 5 to 25 wt % of structural units of a specialized associated monomer having the following structure: wherein Ris a linear saturated Calkyl group; wherein Ris a hydrogen or a methyl group (preferably, wherein Ris a methyl group); and wherein n is an average of 20 to 28; with the proviso that the structural units of the specialized associated monomer (d) are derived from one of (i) a single specialized associated monomer (preferably, a single specialized associated monomer wherein Ris selected from the group consisting of a linear saturated Calkyl group, a linear saturated Calkyl group and a linear saturated Calkyl group; more preferably, a single specialized associated monomer wherein Ris selected from the group consisting of a linear saturated Calkyl group and a linear saturated Calkyl group); (ii) two specialized associated monomers, wherein Ris, respectively, a linear saturated Cand a linear saturated Calkyl group; or (iii) two specialized associated monomers, wherein Ris, respectively, a linear saturated Calkyl group and a linear saturated Calkyl group; (f) 0 to 2 wt % of structural units of multi-ethylenically unsaturated crosslinking monomer or chain transfer agent; and wherein the sum of the weight percentages of structural units (a)-(f) is equal to 100 wt % of the anti-settling, thickening polymer; and method of treating hair or scalp with such a composition. 

Shampoo composition and method of use

An aqueous anti-dandruff shampoo composition which comprises: (I) a cleansing surfactant selected from the group consisting of anionic surfactant, zwitterionic or amphoteric surfactant and nonionic surfactant; (II) suspended particles of an anti-dandruff agent, (III) an anti-settling, thickening polymer, wherein the anti-settling, thickening polymer, comprises: (a) 40 to 74.5 wt % of structural units of Calkyl acrylate; (b) 20 to 50 wt % of structural units of methacrylic acid; (c) 0.2 to &#x3c;5 wt % of structural units of 2-acrylamido-2-methylpropane sulfonic acid (AMPS); (d) 5 to 25 wt % of structural units of a specialized associated monomer having the following structure wherein Ris a linear saturated Calkyl group; wherein Ris a hydrogen or a methyl group (preferably, wherein Ris a methyl group); and wherein n is an average of 20 to 28; with the proviso that the structural units of the specialized associated monomer (d) are derived from one of (i) a single specialized associated monomer (preferably, a single specialized associated monomer wherein Ris selected from the group consisting of a linear saturated Calkyl group, a linear saturated Calkyl group and a linear saturated Calkyl group; more preferably, a single specialized associated monomer wherein R 1 is selected from the group consisting of a linear saturated C12 alkyl group and a linear saturated C18 alkyl group); (ii) two specialized associated monomers, wherein Ris, respectively, a linear saturated Cand a linear saturated Calkyl group; or (iii) two specialized associated monomers, wherein Ris, respectively, a linear saturated Calkyl group and a linear saturated Calkyl group; (e) 0 to 1 wt % of structural units of acrylic acid; and (f) 0 to 2 wt % of structural units of multi-ethylenically unsaturated crosslinking monomer or chain transfer agent; and wherein the sum of the weight percentages of structural units (a)-(f) is equal to 100 wt % of the anti-settling, thickening polymer; and the use of such a composition in a method of treating hair or scalp. 

Antidandruff composition and method of use

A hydrophobically modified rheology modifier comprising:

Hydrophobically modified acrylic rheology modifiers having high carbon number hydrophobes

An SPF booster is provided, comprising: a multistage polymeric particle having a core comprising polymerized units of a monoethylenically unsaturated carboxylic acid core monomer and a non-ionic ethylenically unsaturated core monomer; an inner shell comprising polymerized units of a non-ionic ethylenically unsaturated inner shell monomer; a monoethylenically unsaturated carboxylic acid inner shell monomer and an aliphatic inner shell monomer; an outer shell comprising polymerized units of a non-ionic ethylenically unsaturated outer shell monomer; an aliphatic outer shell monomer; a monoethylenically unsaturated non-carboxylic acid outer shell monomer and an ethylenically unsaturated surfactant outer shell monomer; wherein the core, when dry, contains a void; and wherein the multistage polymeric particle has an average particle size, when dry, of 50 to 1,000 nm.

SPF booster for use in alcohol base sunscreen formulations

A suncare formulation comprising: a dermatologically acceptable organic carrier; a UV radiation absorbing agent; and an SPF booster; wherein the SPF booster comprises a multistage polymeric particle having a core comprising polymerized units of a monoethylenically unsaturated carboxylic acid core monomer and a non-ionic ethylenically unsaturated core monomer; an inner shell comprising polymerized units of a non-ionic ethylenically unsaturated inner shell monomer; a monoethylenically unsaturated carboxylic acid inner shell monomer and an aliphatic inner shell monomer; an outer shell comprising polymerized units of a non-ionic ethylenically unsaturated outer shell monomer; an aliphatic outer shell monomer; a monoethylenically unsaturated non-carboxylic acid outer shell monomer and an ethylenically unsaturated surfactant outer shell monomer; wherein the core, when dry, contains a void; wherein the multistage polymeric particle has an average particle size, when dry, of 50 to 1,000 nm.

Suncare compositions

The present disclosure provides boron-containing diacylhydrazines having Formula I: and the pharmaceutically acceptable salts and solvates thereof, wherein R, R, R, R, and Rare defined as set forth in the specification. The present disclosure also provides the use of boron-containing diacylhydrazines is ecdysone receptor-based inducible gene expression systems. Thus, the present disclosure is useful for applications such as gene therapy, treatment of disease, large scale production of proteins and antibodies, cell-based screening assays, functional genomics, proteomics, metabolomics, and regulation of traits in transgenic organisms, where control of gene expression levels is desirable.

Boron-containing diacylhydrazines

The present disclosure provides crystalline polymorphic and amorphous forms of (R)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N'-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 1) or (S)-3,5-dimethyl-benzoic acid N-(1-tert-butyl-butyl)-N&#x2032;-(2-ethyl-3-methoxy-benzoyl)-hydrazide (Compound 2). The present disclosure further provides compositions comprising crystalline polymorphic and amorphous forms of Compound 1 or Compound 2 and an excipient, methods of making crystalline polymorphic or amorphous forms of Compound 1 or Compound 2, and methods of using crystalline polymorphic or amorphous forms of Compound 1 or Compound 2 to regulate gene expression in a cell or in a subject.

Crystalline diacylhydrazine and the use thereof

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Langhorne, PA, United States of America

Inna Shulman