Symrise Gmbh & Co Kg

Symrise Ag

Prairie Berry Europe Gmbh

Ingo Wöhrle

Jakob Peter Ley

Peter Esser

Aurélia Reckziegel

Walter Kuhn

Thomas Turek

Stephan Klein

Michael Backes

Gerhard Schmaus

Günter Kindel

Arnold Machinek

Michael Krohn

Erich Dilk

Hubert Loges

Tobias Vössing

Marcus Eh

Matthias Brandt

Steffen Sonnenberg

Joachim Hans

Holger Zinke

Hans-Ulrich Funk

Thomas Küper

Jens Bitzer

Bärbel Köpcke

Kathrin Reinhardt

Torsten Grothe

Rita Lages

Axel Schöning

Aurelia Reckziegel

Manfred Meier

Jana Moldenhauer

Christian Ewering

Martin Stürmann

Jörg Mampel

Stephen Klein

Alfred Körber

Jörg Eilers

Bernd Wiedwald

Norbert Andreas Braun

Marinus Cornelius Van Dijk

The present invention relates to certain polyhydroxylated pentacyclic triterpene acids of formula (I) for use as HMG-CoA reductase inhibitors in the prophylactic and/or therapeutic treatment of a disease, disorder or condition that responds to a reduction of the HMG-CoA reductase activity in a mammal, preferably a human being. The present invention further relates to certain mixtures and plant extracts comprising euscaphic acid and tormentic acid, wherein the amount of euscaphic acid to tormentic acid exceeds a certain ratio. Further, the present invention also relates to a formulation, preferably pharmaceutical or nutraceutical formulation, comprising one or more of said compounds of formula (I), a composition according to the present invention or a plant extract according to the present invention. Also, the present invention relates to a process for obtaining certain polyhydroxylated pentacyclic triterpene acids of formula (I), a composition according to the present invention or a plant extract according to the present invention.

Polyhydroxylated pentacyclic triterpene acids as HMG-COA reductase inhibitors

The invention relates to the use of n-hexadecyl n-nonanoate (CAS number 72934-15-7, hereafter cetyl nonanoate) and n-octadecyl n-nonanoate (CAS number 107647-13-2, hereafter stearyl nonanoate) and to the mixtures thereof (CAS number 878027-13-5) as fixatives for fragrance substances. The invention also relates to specific compositions comprising (A) cetyl nonanoate and/or stearyl nonanoate as well as (B) one or more fragrance substances. The invention also relates to a process for the preparation of such compositions as well as to (cosmetic) products comprising a composition according to the invention. The invention further relates to a process for imparting, intensifying or modifying an odor on (human) skin. A particular aspect of the present invention relates to the improvement in the adhesive strength of a composition according to the invention on (human) skin and/or (human) hair.

Compositions comprising fragrance substances and comprising cetyl nonanoate and/or stearyl nonanoate

The present invention relates to the use of a compound or a mixture consisting of two or more compounds or containing one or more compounds selected from the group consisting of compounds of Formulae (I) and (ent-I) wherein in Formulae (I) and (ent-I) the following applies:the aromatic radical Ar is selected from the group consisting of: wherein in the aromatic radicals A and B the following applies:Rand Rare selected independently of one another from the group consisting of H, OH, OCH, OCHCH, OCH(CH), COOCH, COOCHCH, COOCH(CH),or Rand Rare adjacent and jointly form an OCHO group,and wherein in the aromatic radical C the following applies:X is O or Sas a flavoring substance or flavoring substance mixture.

Aromatic neomenthylamides as flavoring substances

The present invention relates to antimicrobially active &#x3c9;-cyclohexylalkan-1-oles of the following formula (I), to a method for producing said compounds and to the use thereof as antimicrobial agents for treating body odor, whereinRto Rindependently of one another denote hydrogen or a linear or branched alkyl radical having 1 to 12 carbon atoms,Rand Rindependently of one another denote hydrogen, a linear or branched alkyl radical having 1 to 6 carbon atoms or a linear or branched alkoxy radical having 1 to 4 carbon atoms, andx is 0 or 1,wherein preferably the total number of carbon atoms in Rto Ris 18 or less.

Omega-cyclohexylalkan-1-oles and use thereof as antimicrobial actives to combat body odor

The present invention relates to the use of 4-methyl-delta-hexylactone for imparting, modifying and/or intensifying one or more smell or flavor impressions from the group consisting of hay, coumarin, lactone and richness in the mouth.

Uses of 4-methyl-5-hydroxy-hexanoic acid lactone

The invention relates to a method for producing cyclohexadecanone by hydrogenating cyclohexadecenone, to mixtures of aromatic substances, and to products containing the inventive cyclohexadecanone.

Method for producing cyclohexadecanone

The present invention relates to supported catalysts based on ReO/(&#x2014;AlOfor use in the preparation of cycloalkadienes in a metathesis reaction, a process for preparing cycloalkadienes in the presence of these supported catalysts and also the use of the resulting cycloalkadienes for preparing fragrances.

Metathesis catalysts

The invention relates to modified supported catalysts based on ReO/&#x3b3;-AlOfor use in the preparation of cycloalkadienes in a metathesis reaction, a process for preparing cycloalkadienes in the presence of these supported catalysts and the use of the resulting cycloalkadienes for the preparation of fragrances.

Modified supported metathesis catalysts

The compound (Z)-7-cyclohexadecen-1-one is described as a musk odorant. Also described are odorant or aroma mixtures comprising (Z)-7-cyclohexadecen-1-one and one or more other odorants or aromas.

(Z)-7-cyclohexadecen-1-one as an odorant

The present invention relates to a process for preparing cycloalkadienes using supported catalysts based on ReO/&#x3b3;-AlOand also to the use of the resulting cycloalkadienes for the preparation of fragrances.

Process for preparing cycloalkadienes

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Holzminden, Germany

Ingo Wöhrle