Schering Aktiengesellschaft

University of Washington

Ingo Tornus

Sven Ring

Gerd Schubert

Walter Elger

Dirk Kosemund

Karl-Heinrich Fritzemeier

Christa Hegele-Hartung

Birgitt Schneider

Olaf Peters

Guenter Kaufmann

Gerd Mueller

Heinz G Floss

Hiroshi Yamanouchi

Sungsook Lee

Compounds of general formula I as well as their pharmaceutically compatible salts are described, in which R stands for hydrogen, C - to C -alkyl, COR , COOR , COSR or CONHR , in which R is C - to C -alkyl or unsubstituted or substituted aryl and in which R is hydrogen, C - to C -alkyl or unsubstituted or substituted aryl, in which R also stands for hydrogen, C - to C -alkyl or C - to C -acyl, and R stands for a C F group, in which n&equals;1, 2 or 3, or a CH O(CH ) C F group, in which m&equals;0 or 1 and n&equals;1, 2 or 3. In addition, a process for the production of the compounds with general formula I is indicated. The compounds can be used for the production of pharmaceutical agents.

17&agr;-fluoroalkyl-11&bgr;-benzaldoxime steroids, process for their production, pharmaceutical preparations that contain these steroids as well as their use for the production of pharmaceutical agents

Use of ER&bgr;-selective ligands for regulating fertility and compounds useful therefor

Disclosed is the compound valiolone, which has the formula (I): ##STR1## a method of preparing valiolone, and a method of using valiolone to prepare acarbose and voglibose.

Valiolone, a method of preparing it, and its use to prepare acarbose and

Growing community of inventors

Hennigsdorf, Germany

Ingo Tornus