Astrazeneca Ab

Almirall, S.a.

Sofotec Gmbh & Co. Kg

Ingo Mett

Gerhard Ludanek

Martin Herder

Joachim Schmidt

Joachim Goede

The invention refers to an inhalation device for powdered drugs to be received by a patient by an inhalation-caused air stream, comprising at least one powder reservoir, metering means for repeatedly metering a powder dose from the reservoir, a transportation mechanism for moving said metering means from a filling position for receiving a powder dose into an emptying position for releasing said powder dose into a powder channel, at least one activating device for manual operation by the patient being operatively connected to said transportation mechanism such that upon operation a single powder dose is being metered, said activating device comprising a dosage key () acting on said transportation mechanism when actuated by the patient. According to the invention, said transportation mechanism furthermore comprises a dosage lever () acting on said metering means, said dosage lever () being locked in the inhalation position of said metering means after said dosage key () has been properly pressed down by the patient. The dosage lever () in the inhalation position engages a trigger member and is releasable by actuation of the trigger member. The trigger member comprises at least one cam surface and the dosage lever () engages the cam surface tangentially in said locked inhalation position.

Inhalation device for powdered drugs

The invention relates to an inhalation device for powdered drugs to be received by a patient by an inhalation-caused air stream, comprising at least one powder reservoir, metering means for repeatedly metering a powder dose from the reservoir, a transportation mechanism for moving said metering means from a filling position for receiving a powder dose into an emptying position for releasing said powder dose into a powder channel, at least one activating device for manual operation by the patient, said activating device being operatively connected to said transportation mechanism such that upon operation a single powder dose is being metered, said activating device comprising a dosage key () acting on said transportation mechanism when pressed by the patient. The inhalation device further comprises an advancing mechanism for advancing a counter means each time the inhalation device has been activated by the patient so that a powder dose has been released into the powder channel. The counter means comprises a mechanical index coupled to a locking mechanism blocking the dosage key () and/or the activating device and/or the transportation mechanism after a predetermined number of metering cycles after detection of the index. Moreover, the locking mechanism includes a locking lever () for positive engagement with the dosage key () and/or the activating device and/or the transportation mechanism in the blocked condition. The inhalation device () is characterized in that the locking lever includes signaling means integrally formed therewith engaging the index after said predetermined number of metering cycles.

The invention relates to an inhalation device for powdered drugs to be received by a patient by an inhalation-caused air stream, comprising at least one powder reservoir, metering means for repeatedly metering a powder dose from the reservoir, a transportation mechanism for moving said metering means from a filling position for receiving a powder dose into an emptying position for releasing said powder dose into a powder channel, at least one activating device for manual operation by the patient, said activating device being operatively connected to said transportation mechanism such that upon operation a single powder dose is being metered, said activating device comprising a dosage key () acting on said transportation mechanism when pressed by the patient. Said dosage key () while being pressed is only temporarily engaged with said transportation mechanism such that a metering cycle while be completed and the transportation mechanism and/or the metering means will be reset even if said dosage key () will be held in depressed condition.

To provide an inhalation device which has improved use properties, particularly advanced moisture protection while in use, an inhalation device () for powder drugs is proposed comprising at least one storage chamber () for accommodating a plurality of drug powder doses and a dosing device which includes at least one dosing slider () which is movable approximately with a translatory movement in a dosing slider passage () at least from a filling position into an emptying position, wherein the inhalation device () further includes a device for inhalation-triggered automatic movement of the dosing slider () from its filling position into the emptying position and a return device for automatic movement of the dosing slider () back into the filling position.

Inhalation device for drugs in powder form

In order to improve the security and reliability of administration of powdered pharmaceuticals through dry powder inhalers, the invention proposes an inhaler () for powdered medicaments, comprising an activating device () for manual engagement by the patient for repeatedly metering a dose of medicament to be administered to the patient, and further comprising an advancing mechanism () for advancing a counter or indexing means () each time the activating device () has been engaged by the patient so that a dose of medicament has been released for administration to the patient, wherein the counter or indexing means () comprises an index (), the index () being detectable by a detection means () of the inhaler, and the detection means () being coupled to a locking mechanism (), the locking mechanism () blocking the activating device () and/or any transportation mechanism () of the inhaler () delayed by a predetermined number of metering cycles since detection of the index (), and a cartridge ().

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Bad Homburg, Germany

Ingo Mett