Ohr Pharmaceutical Inc.

Depymed, Inc.

Cleo Cosmetic and Pharmaceutical Company, LLC

Inez Ruiz-White

Henry Raphael Wolfe

Michael McLane

W Lee Maloy

Henry R Wolfe

Michael Mclane

David B Soll

Teresita M Smith

This application is directed to the use of aminosteroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.

Aminosteroids for the treatment of a PTP1B associated disease

This application is directed to the use of steroid compounds for the selective inhibition of the enzyme PTP1B in a mammal for the treatment of diabetes.

Method for treating diabetes

A corneal storage solution which maintains cell density and cell viability of corneas stored in vitro for a period of greater than four days up to about two weeks is provided. The solution contains a buffered, balanced, nutrient and electrolyte aqueous solution, at least one colloidal osmotic agent, a phenolic antioxidant compound, a non-lactate-generating substrate, a thiol-containing compound, insulin, and at least one antibiotic. A method for in vitro storage and preservation of the viability of human corneal endothelial cells for subsequent use includes the steps of removing a cornea from an eye globe and placing the cornea in the above corneal storage solution.

Composition using HMW dextran and method for in vitro preservation of corneal tissues

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Mount Laurel, NJ, United States of America

Inez Ruiz-White