Other

The University of Texas System

Sensulin, LLC

University of Houston System

Texas Children's Hospital

Alzeca Biosciences, LLC

Indrani Dasgupta

Ananth V Annapragada

Eric A Tanifum

Stephen C Cook

Jason Eriksen

Mayank Srivastava

Mostafa Analoui

Jason L Eriksen

Ananth Annapragada

Eric Tanifum

Lipid-based nanoparticle compositions are provided. The compositions generally comprise lipid-hydrophilic polymer-amyloid binding ligand conjugates, and may be liposomal compositions. The compositions, including the liposomal compositions, may be useful for imaging and/or the treatment of amyloid-&#x3b2; plaque deposits characteristic of Alzheimer's Disease.

Lipid-based nanoparticles

Vesicle compositions are provided that comprise a therapeutic compound. The vesicle compositions may be capable of releasing the therapeutic compound in response to the presence of an external trigger. The vesicle compositions may comprise a plurality of biocompatible vesicles. The biocompatible vesicles may comprise a therapeutic compound for treatment of a patient in need thereof, and one or more cross-linkages between two or more of the biocompatible vesicles, each cross-linkage comprising a chemical sensing moiety and a sensed moiety. In some embodiments, the therapeutic compound may be any compound that provides palliative, curative, or otherwise beneficial effects to a patent.

Vesicle compositions

Growing community of inventors

Frederick, MD, United States of America

Indrani Dasgupta