Osong Medical Innovation Foundation, Korea University Research and Business Foundation

Kookmin University

In-Sik Hwang

Sunghoi Hong

Kyung-A Choi

Seung-Jin Heo

Il-Hwan Kim

Jay-Il Jeong

Hang-Soo Park

Jay-II Jeong

II-Hwan Kim

The present invention relates to a composition for stimulating hair growth or preventing hair loss, which contains a conditioned medium or extract of neural stem cells (NSCs) isolated from the ventricular zone of the human brain, and to a preparation method thereof. The conditioned medium or extract of neural stem cells according to the present invention contains various growth factors and cytokines, and thus has an excellent effect on the stimulation of hair growth. Thus, it is useful for hair growth stimulation and hair loss prevention.

Composition for stimulating hair growth or preventing hair loss which includes extract neural stem cell and method for producing same

The present invention relates to a composition for maintaining the chromosomal stability of pluripotent stem cells, which contains a small-molecule compound, and more particularly, to a composition for maintaining the chromosomal stability of induced pluripotent stem cells, which contains a ROCK inhibitor, a MEK inhibitor, an ALK5 inhibitor or an antioxidant, which is capable of inhibiting chromosomal structural and numerical mutations or DNA damage during induction of induced pluripotent stem cell and the subsequent culture of the cells. The small-molecule compound-containing composition for maintaining the chromosomal stability of induced pluripotent stem cells increases the reprogramming rate and efficiency during production of induced pluripotent stem cells and exhibits excellent effects on the inhibition of chromosomal structural and numerical mutations or DNA damage. Thus, the composition of the present invention is very useful for the development of induced pluripotent stem cell therapeutic agents having excellent chromosomal stability.

Composition for maintaining chromosomal stability of pluripotent stem cells, containing small-molecule compounds

Provided is a sunroof apparatus of the present invention including a sunroof panel that divides a roof panel, except for left and right side fillers of the roof of a vehicle, into a front panel, a middle panel, and a rear panel, and link units composed of an interlink that moves middle panel by the operation of a driving link moving rear panel and a driven link that moves front panel by the operation of interlink, such that all of the portions, except for left and right side fillers of the roof of the vehicle are completely opened while rear panel, middle panel, and front panel are folded in several steps and horizontally stacked when the sunroof is opened, such that open feel, which is maximized like a convertible vehicle.

Horizontal folding type sunroof apparatus

A sunroof mounting device is provided, which includes guide rails of which the entire width is reduced by a pair of first and second guiders arranged up and down such that a moving-connecting portion connected to a sunroof is vertically combined in an open space from a side, such that the space opened by the sunroof is not covered by guide rails and improved open feel.

Growing community of inventors

Seoul, South Korea

In-Sik Hwang