Kyungpook National University Industry-Academic Cooperation Foundation

In-Seop So

Soyoun Kim

In San Kim

In-San Kim

Byung-Heon Lee

Kiweon Cha

Eunsung Jun

Jaeog Jeon

Sun-Ji Kim

A fusion polypeptide, including a first polypeptide fragment including 5 to 30 amino acids, the first polypetide fragment is fused between a first amino acid and a fifth amino acid of a fourth loop of a human-derived ferritin monomer.

Human ferritin-derived fusion polypeptide

The present invention relates to a novel protein skeletal module which increases the binding affinity or binding specificity of active polypeptides. More particularly, the present invention relates to a protein skeletal module comprising polypeptides consisting of the 1to 19amino acids of the amino acid sequence expressed in sequence number 1; polypeptides comprising active polypeptides; and polypeptides consisting of the 29to 86amino acids of the amino acid sequence expressed in sequence number 1. The present invention also relates to a method for preparing the protein skeletal module. The protein skeletal module of the present invention increases the binding affinity or binding specificity of active polypeptides embedded therein, and therefore is effective in diagnosing and treating diseases.

Protein skeletal module which increases the binding affinity and binding specificity of active polypeptides

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Daegu, South Korea

In-Seop So