Bioapplications Inc.

Postech Academy-Industry Foundation

Republic of Korea (Animal and Plant Quarantine Agency)

Biocompanion Inc.

In Hwan Hwang

Hyang Ju Kang

Jun Ho Lee

Yong Jik Lee

Eun Ju Sohn

Dong Jun An

Nam Hyung Kim

Hye Young Jeoung

Sung Min Gu

Selvan Thangarasu Muthamil

Shijian Song

Jae Young Song

Seong In Lim

Nam Jo Park

Dong Wook Lee

Madhu Kumari

Bong Ryul Ryu

Abdur Razzakmd

The present invention relates to a method for mass-producing a target protein in a plant and, more specifically, to a method for producing high levels of protein in plant leaf cells, in which an expression cassette construct for high expression of a target gene and an expression cassette construct for high expression of p38 as a gene silencing suppressor, are prepared, a binary vector for transient expression in plant cells, having the construct together, is then prepared, and the binary vector is then subjected to-mediated transformation by using a singleculture.

Method for mass production of target protein in plant

Provided is a technique for highly expressing a target protein in a plant cell by using a glycosylation domain, a recombinant vector comprising a gene encoding a fusion protein of a glycosylation domain and a target protein, a recombinant cell, a transformed plant, and a method of producing a target protein using these.

Recombinant vector for expressing target protein in plant cell

A recombinant vector for transforming a plant, a plant transformed with the recombinant vector, a plant-made classical swine fever virus antigen pmE2 protein expressed in the plant and uses thereof is provided. By using a recombinant vector having a polynucleotide encoding a GP55 protein of CSFV according to the present invention; and a polynucleotide encoding a cellulose-binding domain protein; and a plant transformed with the recombinant vector, a plant-made classical swine fever virus antigen pmE2 protein may be produced with high efficiency, and has higher safety and stability than those achieved by other production methods. Also, since the plant-derived classical swine fever virus antigen protein pmE2 has a cellulose-binding domain (CBD) protein, it may be usefully used as an effective marker to determine a virus exposure pathway and an antibody producing pathway.

Vaccine composition for classical swine fever from plant and manufacturing method thereof

Growing community of inventors

Pohang-si, South Korea

In Hwan Hwang