Cj Cheiljedang Corporation

In Hwa Yoo

Hye Won Kim

Sol Kim

Jin Sook Chang

Jong Hyun Kim

Min Gyeong Kang

The present invention relates to an RhtB (homoserine/homoserine lactone export transporter) protein variant having an enhanced ability to export O-phosphoserine (OPS) that is a precursor of L-cysteine, a polynucleotide encoding the protein, a vector comprising the polynucleotide, an OPS-producing microorganism comprising the protein variant, a method of producing O-phosphoserine using the microorganism, and a method for preparing cysteine or its derivatives, which comprises reacting O-phosphoserine, produced by the method above, with a sulfide in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism that expresses OPSS.

RHTB protein variants and the method of producing O-phosphoserine using the same

The present disclosure relates to a novel polypeptide having O-phosphoserine (OPS) exporting activity, a polynucleotide encoding the polypeptide, a microorganism expressing the polypeptide, a method for producing OPS using the microorganism, and a method for producing cysteine or a derivative thereof comprising reacting the O-phosphoserine produced by the same with a sulfide, in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism expressing the same.

Variant of O-phosphoserine exporter and method of producing O-phosphoserine, cysteine, and its derivatives using the same

RhtB protein variants and the method of producing O-phosphoserine using the same

The present invention relates to a microorganism, wherein the activity of a polypeptide capable of exporting O-phosphoserine (OPS) is enhanced, and a method of producing O-phosphoserine, cysteine, or a cysteine derivative using the microorganism.

Microorganism producing O-phosphoserine and a method for producing O-phosphoserine or L-cysteine using the same

The present invention relates to a novel isolated polypeptide having the ability to export O-phosphoserine (OPS) that is a precursor of L-cysteine, a vector comprising the polynucleotide, an OPS-producing microorganism having enhanced activity of the polypeptide, a method of producing OPS using the microorganism, and a method for preparing cysteine or its derivatives, which comprises reacting OPS, produced by the above method, with a sulfide in the presence of O-phosphoserine sulfhydrylase (OPSS) or a microorganism that expresses OPSS.

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Incheon, South Korea

In Hwa Yoo