Chonnam National University

In-Ho Bae

Myung Ho Jeong

Eun Jae Jang

Kyung Seob Lim

Dae Sung Park

So Youn Lee

Jun Kyu Park

Jae Won Shim

In Soo Kim

Doo Sun Sim

A tacrolimus drug-eluting stent manufacturing method according to the present invention enables a tacrolimus drug to be strongly and stably bound onto a stent, while also not necessarily involving a separate step of introducing a surface-binding functional group for the binding of a drug onto a stent and a step of introducing, into the drug, a functional group capable of binding to the surface-binding functional group, and a tacrolimus drug-eluting stent manufactured by the manufacturing method has a greater total drug elution amount and has a more excellent delayed drug-elution property.

Non-polymeric tacrolimus drug-eluting stent and manufacturing method therefor

Provided is a drug-eluting coronary stent. In the drug-eluting coronary stent according to the present invention, electrospinning is used, thereby making it possible to precisely control a total content of an everolimus-based drug bound thereto and form a uniform layer in spite of not using a polymer causing late thrombosis, or the like.

Method of manufacturing polymer-free everolimus-eluting coronary stent fabricated by electrospinning technique

Provided are a peptide compound prepared by additional synthesis in a drug having an effect of inhibiting restenosis, a composition for inhibiting restenosis and promoting re-endothelialization including the peptide compound, and a stent having a surface coated by using the composition, in order to overcome a restenosis problem in the stent.

Peptide compound for inhibiting restenosis and promoting re-endothelialization and method for preparing the same

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Gwangju, South Korea

In-Ho Bae