Lg Chemical Ltd.

Lg Life Sciences, Limited

In Ae Ahn

Hyun Min Lee

Jong Sung Koh

Jong Hyun Kim

Sun Hwa Lee

Koo Lee

Sung Pil Choi

Soo Yong Chung

Sang Dae Lee

You Seung Shin

Seong Gu Ro

Hyun Sung Kim

Hyun Il Lee

Hyun Ho Chung

Tae Hwan Kwak

Tae Saeng Choi

Dong Sup Shim

Kwi Hwa Kim

Jin Ho Lee

Sang Pil Moon

Won Hee Jung

Hyun Ho Lee

Shin Wu Jeong

Jung Kwon Yoo

Young Kwan Kim

Hyeon Joo Yim

Deog Young Choi

Young Hoon Oh

Yong Hwa Ha

Jung Ae Lee

Youn Hoa Kim

Sang Hyup Lee

Chung Mi Kim

Mi Sook Shin

Oeuk Park

Min Kyung Yoon

The present invention relates to a compound having a good agonistic activity to melanocortin receptor, or pharmaceutically acceptable salt or isomer thereof, and an agonistic composition for melanocortin receptor comprising the same as an active ingredient.

Melanocortin receptor agonists

The present invention relates to a compound of the following formula 1, pharmaceutically acceptable salt and isomer thereof effective as agonist of melanocortin receptor, and an agonistic composition of melanocortin receptor comprising the same as active ingredient.

The present invention relates to novel imidazole derivatives which show an inhibitory activity against farnesyl transferase, pharmaceutically acceptable salts or isomers thereof and pharmaceutical compositions comprising such imidazole derivatives. More particularly, the present invention relates to intermediate compounds which are used in the preparation of the imidazole derivatives of the invention. Related processes also are disclosed.

Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof

The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, n and Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1): and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.

Farnesyl transferase inhibitors having a piperidine structure and process for preparation thereof

The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, n,and Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.

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Daejeon, South Korea

In Ae Ahn