Hoffmann-La Roche Inc.

Imke Sonja Ludwig

Hanns-Christian Mahler

Tobias Werk

Jörg Lümkemann

Carmen Lema Martinez

Joerg Luemkemann

Tim Dreckmann

Denis Luthringer

Julien Boeuf

Anke Dorn

A process of assembling a filling system for low volume filling of a liquid into a container is disclosed. The process includes obtaining plural liquid forwarding devices configured to provide the liquid from a reservoir to the container, and simulating operation of each of the liquid forwarding devices by numerically modelling flow patterns of the liquid when being forwarded by the liquid forwarding devices, and by determining a shear stress rate for each of the liquid forwarding devices based on the modelled flow patterns. The process further includes determining an appropriateness for each of the liquid forwarding devices by comparing operation parameters of the liquid forwarding of the liquid forwarding devices, wherein the operation parameters include the determined shear stress rates, selecting the liquid forwarding device having the highest determined appropriateness, and installing the selected liquid forwarding device into the filling system.

Low volume filling of a liquid into a container

An inspection device has a particle detector adapted to detect particles in a liquid, the particle detector preferably including a camera. The inspection device including a seat adapted to position a container housing the liquid in an area of operation of the particle detector and a vibration arrangement for vibrating the container. The vibration arrangement includes a frequency generator adapted to provide an electrical signal and a transducer adapted to transduce the electrical signal provided by the frequency generator into an acoustic wave. The seat is adapted to position the container adjacent to the transducer for inspecting a liquid inside a container with respect to the existence of particles. The inspection device allows for an accurate and gentle inspection of the liquid filled in the container and for detecting particles in the liquid.

Vibrating inspection device for detection of particles in a liquid

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Basel, Switzerland

Imke Sonja Ludwig