Nanoco Technologies Limited

Life Technologies Corporation

Invitrogen Corporation

Samsung Electronics Co., Ltd.

Biocrystal, Ltd.

Nanaco Technologies Ltd.

Imad Naasani

Cong-Duan Vo

Nigel Pickett

James Harris

Amilcar Pillay Narrainen

Eric Tulsky

John Matthew Mauro

Joseph A Treadway

Kari N Haley

Roman Rozhkov

Theo Nikiforov

Joseph M Beechem

Dmitriy Gremyachinskiy

Daniel Mazur

Xinzhan Peng

Yuri Belosludtsev

Howard Reese

Hao Pang

Tommie Lloyd Lincecum

Emma Cherie Hogarth

Ombretta Masala

Abu Mohammad Imroz Ali

Ross Mera-Pirttijarvi

James Gillies

Xiaojuan Wang

Siobhan S Daniels

Emma Fitzgerald

Yien Ta

Alexandra Shannon

Elliot Stuart Poucher

Bruce Branchaud

Nathalie C Gresty

Eric Welch

Mark C McCairn

Paul Chalker

Matthew Werner

Nigel Picket

Tommie Lloyd Lincecum, Jr

Khai Duong Quang Nguyen

Xioajuan Wang

Joeseph A Treadway

Multi-phase polymer films containing quantum dots (QDs) are described herein. The films have domains of primarily hydrophobic polymer and domains of primarily hydrophilic polymer. QDs, being generally more stable within a hydrophobic matrix, are dispersed primarily within the hydrophobic domains of the films. The hydrophilic domains tend to be effective at excluding oxygen.

Quantum dot films utilizing multi-phase resins

Surface-modified nanoparticles are produced by associating ligand interactive agents with the surface of a nanoparticle. The ligand interactive agents are bound to surface modifying ligands that are tailored to impart particular solubility and/or compatibility properties. The ligand interactive agents are crosslinked via a linking/crosslinking agent. The linking/crosslinking agent may provide a binding site for binding the surface modifying ligands to the ligand interactive agents.

Surface modified nanoparticles

Disclosed herein are conjugates comprising a biomolecule linked to a label that have biological activity and are useful in a wide variety of biological applications. For example, provided herein are polymerase-nanoparticle conjugates including a polymerase linked to a nanoparticle, wherein the conjugate has polymerase activity. Such conjugates can exhibit reduced aggregation and improved stochiometries wherein the average biomolecule:nanoparticle ratio approaches or equals 1:1. Also disclosed herein are improved methods for preparing such conjugates, and methods and systems for using such conjugates in biological applications such as nucleotide incorporation, primer extension and single molecule sequencing.

Conjugates of biomolecules to nanoparticles

Highly stable films containing semiconductor nanoparticles ('quantum dots') are prepared from resins containing a fast-curing inner phase having a high glass transition temperature (T) and certain inner phase/outer phase combinations. The resins may comprise an inner phase and outer phase (but may appear to be a single phase due to their homogeneous appearance when viewed using an optical microscope). The method provides a highly scalable and cost-effective procedure for preparing films that are resistant to light, elevated temperatures, moisture, and oxygen.

Highly stable quantum DOT-containing polymer films

Surface-modified nanoparticles are produced by associating ligand interactive agents with the surface of a nanoparticle. The ligand interactive agents are bound to surface modifying ligands that are tailored to impart particular solubility and/or compatibility properties. The ligand interactive agents are crosslinked via a linking/crosslinking agent, such as hexamethoxymethylmelamine or a derivative thereof. The linking/crosslinking agent may provide a binding site for binding the surface modifying ligands to the ligand interactive agents.

A light emitting layer including a plurality of light emitting particles embedded within a host matrix material. Each of said light emitting particles includes a population of semiconductor nanoparticles embedded within a polymeric encapsulation medium. A method of fabricating a light emitting layer comprising a plurality of light emitting particles embedded within a host matrix material, each of said light emitting particles comprising a population of semiconductor nanoparticles embedded within a polymeric encapsulation medium. The method comprises providing a dispersion containing said light emitting particles, depositing said dispersion to form a film, and processing said film to produce said light emitting layer.

Semiconductor nanoparticle-based light emitting materials

Compositions and methods are described for delivery of drugs to desired tissues via soluble quantum dots.

Light responsive quantum dot drug delivery system

A molded nanoparticle phosphor for light emitting applications is fabricated by converting a suspension of nanoparticles in a matrix material precursor into a molded nanoparticle phosphor. The matrix material can be any material in which the nanoparticles are dispersible and which is moldable. The molded nanoparticle phosphor can be formed from the matrix material precursor/nanoparticle suspension using any molding technique, such as polymerization molding, contact molding, extrusion molding, injection molding, for example. Once molded, the molded nanoparticle phosphor can be coated with a gas barrier material, for example, a polymer, metal oxide, metal nitride or a glass. The barrier-coated molded nanoparticle phosphor can be utilized in a light-emitting device, such as an LED. For example, the phosphor can be incorporated into the packaging of a standard solid state LED and used to down-convert a portion of the emission of the solid state LED emitter.

Molded nanoparticle phosphor for light emitting applications

The surfaces of nanoparticles (QDs) are modified with amphiphilic macromolecules, for example, amphiphilic copolymers. The surface modification renders the QDs more compatible with oxygen-excluding matrices, such as epoxy resin, polyurethane resin, polyester resins or any hydrophilic inorganic/organic hybrid resin such as (meth)acrylate-functionalized polyhedral oligomeric silsesquioxane (POSS).

Surface-modified nanoparticles

Highly stable quantum dot-containing polymer films

Growing community of inventors

Manchester, United Kingdom

Imad Naasani