Rutgers, the State University of New Jersey

Phyto Tech Corp.

Other

Edenspace Systems Corporation

Ilya Raskin

Nanda P Kumar

Slavik Douchenkov

Yoram Kapulnik

David M Ribnicky

Nebojsa Ilic

Burt D Ensley

Alexander A Poulev

Diana Roopchand

Mykola Borysyuk

Lyudmyla Borysyuk

Ilan Chet

Natalia Pogrebnyak

Slavik Dushenkov

Brittany Graf

Peter Kuhn

Shoshan Haran

Moul Dey

David Salt

Christophe Ripoll

David E Salt

Michael Blaylock

Joseph M O'Neal, Iii

Diana Cheng

Carrie Waterman

Slavko Komarnytsky

Jonathan Gorelick-Feldman

Barbara Schmidt

The present application is directed to materials and methods for producing extracts from a plant of the Moringaceae family having high concentrations ofisothiocyanates.

Extracts from plants of the Moringaceae family and methods of making

Described herein is an enriched substance containing a ground edible material comprising one or more concentrated bioactive natural products from plant juice, as well as methods of producing such enriched substances and methods of using such solids to provide beneficial effects to humans or other animals. Enriched foods comprising the enriched substance(s) are also provided. Also provided are non-sorbed natural products such as sugars, fats oils, and carotenoids found in the non-sorbed plant liquor fraction of plant juice.

Methods of obtaining natural products from the comestible fluids and methods of use

The present disclosure provides methods for the production of enriched substances that can be used in the preparation of enriched food products, dietary supplements, medical foods, cosmetic products or pharmaceutical agents.

Production of enriched products

The present application is directed to materials and method for producing leachates from a plant of the Amaranthaceae family.

Methods of making quinoa leachates and uses thereof

Provided herein are several improved lettuce varieties, having increased anthocyanin and polyphenol content, and increased oxygen radical absorption capacity, as compared to other known varieties of lettuce. Also provided are parts of such new lettuces, such as leaves, heads, seeds, tissue cultures, and extracts generated from such varieties. The disclosure also provides methods of using the new lettuces and parts thereof, for example to reduce blood glucose levels.

Red lettuces with increased anthocyanins, polyphenols, and oxygen radical absorption capacity

This invention relates to methods and compositions which are useful in the modulation of endogenous growth hormone levels in a mammal. Also included are methods of treating a mammal which include the administration of said compositions.

Methods for treating or preventing disorders using ecdysteroid compositions

The invention relates to methods of reducing circulating glucose levels with compositions obtained from botanical sources. More specifically, the invention relates to methods of treating individuals whom wish to reduce their circulating glucose levels, particularly individuals having elevated circulating glucose levels, with an extract product of

Methods for reducing circulating glucose levels

The subject of this invention is the anti-inflammatory activity of a formulation of(upland cress, early winter cress, or winter cress) seed preparation (BSP) containing phenethylisothiocyanate as its main active ingredient. BSP is a promising anti-inflammatory agent, which can be used for treatment of many inflammation-related conditions, including but not limited to rheumatoid and osteoarthritis, acute and chronic pains, lupus, irritable bowl disease, cancer and metabolic syndrome.

[object Object]

The invention relates to appetite-suppressing compositions obtained from botanical sources. More specifically, the invention relates to appetite-suppressing compositions comprising an extract product of anplant, methods of making an appetite-suppressing composition, and methods of suppressing an appetite.

Appetite-suppressing compositions and methods

A method of preparing a chicory extract enriched with sesquiterpene lactones is provided. The method includes performing an initial extraction chicory in a polar solvent, such as methanol or ethanol, at ambient temperature to form an alcoholic extract. The alcoholic extract is subsequently defatted with a non-polar solvent, preferably hexane or n-heptane. A second extraction of the defatted alcoholic extract is performed with a solvent which is more polar than the solvent used in the defatting process and less polar than the solvent used in the initial extraction, for example, it can be chosen from the group consisting of ethyl acetate, n-butanol, isopropanol, n-propanol, dichloromethane, acetonitrile, and mixtures thereof; resulting in a sesquiterpene lactones enriched extract, preferably containing at least 60% sesquiterpene lactones.

Substances having antiviral activity against one or more human disease-causing viruses are disclosed. These antiviral substances are obtained from the cuticular and extracuticular layers of plants. Pharmaceutical and nutraceutical formulations comprising the antiviral substances are also disclosed, as are methods of using such formulations to treat viral diseases.

Antiviral substances from plant cuticular and epicuticular material

The present disclosure provides methods for obtaining gaultherin, a natural salicylate derivative, from plant tissue. The methods involve preventing the hydrolysis of the gaultherin in the plant tissue by disrupting the plant tissue under solvent conditions lacking a drying agent. The disclosure further provides various forms of plant-derived gaultherin, including alcoholic extracts, aqueous solutions and dried preparations, all suitable for use as a natural aspirin substitute. Moreover, the disclosure provides methods of using gaultherin-containing compositions to increase serum salicylic acid, to treat cancer cells, to treat cardiovascular (e.g., cardiopulmonary) conditions, to treat anti-inflammatory responses, and to inhibit cyclooxygenase.

Methods of administering gaultherin-containing compositions

The present invention provides materials and methods relating to mildly polar fluid extracts of plant materials, such asplant species, useful in methods for treating diabetes and methods for modulating the activity of glucagon-like peptide-1 (GLP-1), and in methods for modulating phosphoenol pyruvate carboxykinase (PEPCK) activity in a diabetes-specific manner. The extracts are generally non-toxic and non-mutagenic and may be administered to diabetics with beneficial effect on blood glucose levels. The extracts may also be administered to non-diabetics without deleterious effect. The plants are easily grown with a minimum of time, labor, and cost. Extracts are inexpensively and quickly prepared without the need for fractionation to remove potentially deleterious compounds, and the extracts may be administered to mammals such as humans through various routes, in a variety of forms, and at convenient concentrations.

Method for treating type 2 diabetes with an extract of Artemisia

Materials and methods relating to the use of phosphorus-controllable plant promoters to express operably linked polynucleotides in plant cells, intact plant portions or whole plants, and the optional recovery of the expressed polypeptides, are disclosed. The materials of the invention are the recombinant expression units including a phosphorus-controllable plant promoter and an operably linked, non-native, polynucleotide coding region. The methods of the invention use plant materials that are intact, living and capable of secreting (plant cells) or exuding (intact plant portions and whole plants) the expressed polypeptides. The methods of the invention minimize operator intervention and exploit solar energy and the minimal nutrient needs of photoautotrophic organisms to provide inexpensive and indefinitely sustainable methods for controllably producing a variety of coding region products.

Phosphorus-controllable recombinant expression of polypeptides in plants

Products and methods for amplifying target nucleic acids using cells derived from plants are disclosed. Also disclosed are methods for improving transcription of target nucleic acids beyond expectations based solely on target copy number, and the recovery of such expression products. The products include nucleic acids containing a plant-active Amplification Promoting Sequence (APS) and the methods exploit these products in amplifying target nucleic acids. The methods of the invention minimize operator intervention and exploit solar energy and the minimal nutrient needs of photoautotrophic organisms to provide inexpensive and indefinitely sustainable methods for producing a variety of amplified target nucleic acids and encoded products such as polypeptides.

Growing community of inventors

Manalapan, NJ, United States of America

Ilya Raskin